Acrylamide

Acrylamide

SCHEMBL28201834

C=C(C)C(N)=O.C=CC(N)=O.C=CCNC(=O)C=C

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.43
TSHR P16473 5/20 0.42
ALDH1A1 P00352 3/20 0.42
MAPK1 P28482 1/20 0.42
FGFR4 P22455 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.37
MAPT P10636 1/20 0.37
ZDHHC20 Q5W0Z9 1/20 0.37
ZDHHC2 Q9UIJ5 1/20 0.37
KMT2A Q03164 1/20 0.35
FAAH O00519 1/20 0.35
RAB9A P51151 2/20 0.35
NPC1 O15118 1/20 0.35
KDM4E B2RXH2 2/20 0.33
PKM P14618 1/20 0.32
TGM2 P21980 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylamide SCHEMBL9362700 0.89 ALDH1A1 (0.52) TDP1TSHRALDH1A1MAPK1FGFR4
SCHEMBL4843584 0.81 TSHR (0.45) TDP1TSHRALDH1A1MAPK1SMN1; SMN2
SCHEMBL9238864 0.81 TDP1 (0.50) TDP1TSHRALDH1A1MAPK1FGFR4
SCHEMBL8037505 0.81 ALDH1A1 (0.67) TDP1TSHRALDH1A1MAPK1FGFR4
SCHEMBL30851 0.80
SCHEMBL2191231 0.79 TDP1 (0.48) TDP1TSHRALDH1A1MAPK1FGFR4
SCHEMBL27993233 0.79 TDP1 (0.48) TDP1TSHRALDH1A1MAPK1FGFR4
Acrylic Acid SCHEMBL28104412 0.79 TDP1 (0.40) TDP1TSHRALDH1A1MAPK1FGFR4
Dimethylamine SCHEMBL3821887 0.78 TSHR (0.54) TDP1TSHRALDH1A1MAPK1SMN1; SMN2
Ammonia Solution, Strong SCHEMBL1076016 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107615062-A Hydrogel particles with tunable optical properties and methods of using the same 弹弓生物科学公司 2018-01-19 CN disclosed