Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | TOP1 | P11387 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2819012 | 0.88 | MAPK13 (0.51) | XDHSLC22A12ALDH1A1RAB9ANPC1 | |
| SCHEMBL2824946 | 0.86 | XDH (0.48) | XDHSLC22A12ALDH1A1RAB9ANPSR1 | |
| SCHEMBL2818647 | 0.85 | XDH (0.48) | XDHSLC22A12ALDH1A1RAB9APOLB | |
| SCHEMBL2822421 | 0.85 | XDH (0.50) | XDHSLC22A12ALDH1A1RAB9ANPSR1 | |
| SCHEMBL2822721 | 0.81 | XDH (0.52) | XDHSLC22A12ALDH1A1RAB9ANPSR1 | |
| SCHEMBL2819006 | 0.80 | XDH (0.48) | XDHSLC22A12ALDH1A1RAB9ANPC1 | |
| SCHEMBL2824998 | 0.80 | XDH (0.48) | XDHSLC22A12ALDH1A1RAB9ANPC1 | |
| SCHEMBL2820132 | 0.80 | MAPT (0.53) | XDHSLC22A12ALDH1A1RAB9ANPSR1 | |
| SCHEMBL2819678 | 0.70 | MAPT (0.62) | XDHSLC22A12ALDH1A1RAB9ANPC1 | |
| SCHEMBL2818742 | 0.69 | SMO (0.58) | XDHSLC22A12ALDH1A1RAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1789044-B1 | PHENYLAMINOPYRIDINES AND PHENYLAMINOPYRAZINES | BASILEA PHARMACEUTICA AG (CH) | 2010-10-27 | — | — | EP | claimed |