Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4845510 | 0.84 | AR (0.51) | ARPIK3CDPIK3CAPIK3CBSMN1; SMN2 | |
| SCHEMBL15349299 | 0.84 | AR (0.51) | ARPIK3CDPIK3CAPIK3CBSMN1; SMN2 | |
| SCHEMBL6281444 | 0.81 | AR (0.49) | ARPIK3CDPIK3CAPIK3CBSMN1; SMN2 | |
| SCHEMBL4851509 | 0.78 | ALDH1A1 (0.50) | ARPIK3CDPIK3CAPIK3CBSMN1; SMN2 | |
| SCHEMBL4850658 | 0.78 | PIK3CD (0.61) | ARPIK3CDPIK3CAPIK3CBSMN1; SMN2 | |
| SCHEMBL15925460 | 0.77 | AR (0.51) | ARPIK3CDPIK3CAPIK3CBSMN1; SMN2 | |
| SCHEMBL19034737 | 0.76 | AR (0.44) | ARPIK3CDPIK3CAPIK3CBSMN1; SMN2 | |
| SCHEMBL7922690 | 0.76 | ALDH1A1 (0.51) | ARPIK3CDPIK3CAPIK3CBSMN1; SMN2 | |
| SCHEMBL626001 | 0.76 | PIK3CA (0.52) | PIK3CDPIK3CAPIK3CBSMN1; SMN2MAPT | |
| SCHEMBL15925462 | 0.75 | SMN1; SMN2 (0.49) | ARPIK3CDPIK3CAPIK3CBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107602589-A | A kind of preparation method of compound | 中国药科大学 | 2018-01-19 | — | — | CN | disclosed |