Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15349299 | 0.88 | AR (0.51) | ARPIK3CDPIK3CAPIK3CBSMN1; SMN2 | |
| SCHEMBL7922424 | 0.83 | PPARG (0.41) | ARALDH1A1PPARGPPARARAB9A | |
| SCHEMBL28202094 | 0.81 | AR (0.51) | ARPIK3CDPIK3CAPIK3CBSMN1; SMN2 | |
| SCHEMBL4845510 | 0.81 | AR (0.51) | ARPIK3CDPIK3CAPIK3CBSMN1; SMN2 | |
| SCHEMBL4851509 | 0.78 | ALDH1A1 (0.50) | ARPIK3CDPIK3CAPIK3CBSMN1; SMN2 | |
| SCHEMBL7922690 | 0.76 | ALDH1A1 (0.51) | ARPIK3CDPIK3CAPIK3CBSMN1; SMN2 | |
| SCHEMBL4057611 | 0.76 | TRPV3 (0.36) | SMN1; SMN2PPARGPPARARAB9ANPC1 | |
| SCHEMBL4850658 | 0.75 | PIK3CD (0.61) | ARPIK3CDPIK3CAPIK3CBSMN1; SMN2 | |
| SCHEMBL4889147 | 0.74 | ALDH1A1 (0.53) | ARPIK3CDPIK3CAPIK3CBALDH1A1 | |
| SCHEMBL15925460 | 0.74 | AR (0.51) | ARPIK3CDPIK3CAPIK3CBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6933309-B2 | Halogenobenzyl aminopropionic acid derivatives | TOAEIYO LTD. (JP) | 2005-08-23 | — | — | US | disclosed |
| EP-1466909-A1 | HALOGENOBENZYL AMINOPROPIONIC ACID DERIVATIVES | Toaeiyo Ltd. (JP) | 2004-10-13 | — | — | EP | disclosed |
| US-20040102439-A1 | Halogenobenzyl aminopropionic acid derivatives | TOAEIYO LTD. (JP) | 2004-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102439-A1 | Halogenobenzyl aminopropionic acid derivatives | FABP4, SLC5A1, ALDH7A1 | AR 1981/4885PIK3CD 1452/4885PIK3CA 1674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.