Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.54 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.51 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.51 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.51 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.48 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 6/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6414021 | 0.87 | EPHX2 (0.50) | EPHX2GNAI3GNAO1GNAI1S1PR4 | |
| SCHEMBL11499799 | 0.83 | THRB (0.57) | — | |
| SCHEMBL5013508 | 0.81 | EPHX2 (0.47) | EPHX2GNAI3GNAO1GNAI1EPHX1 | |
| SCHEMBL7593415 | 0.80 | GNAI3 (0.55) | EPHX2GNAI3GNAO1GNAI1S1PR4 | |
| SCHEMBL24803090 | 0.79 | GNAI3 (0.58) | EPHX2GNAI3GNAO1GNAI1S1PR4 | |
| SCHEMBL21949297 | 0.79 | GNAI3 (0.58) | EPHX2GNAI3GNAO1GNAI1S1PR4 | |
| SCHEMBL31066862 | 0.79 | GNAI3 (0.58) | EPHX2GNAI3GNAO1GNAI1S1PR4 | |
| SCHEMBL31066865 | 0.79 | GNAI3 (0.58) | EPHX2GNAI3GNAO1GNAI1S1PR4 | |
| SCHEMBL8945388 | 0.79 | GNAI3 (0.53) | EPHX2GNAI3GNAO1GNAI1S1PR4 | |
| SCHEMBL31066880 | 0.79 | GNAI3 (0.58) | EPHX2GNAI3GNAO1GNAI1S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109963842-A | Benzimidazoles compound kinase inhibitor and its preparation method and application | 江苏豪森药业集团有限公司 | 2019-07-02 | — | — | CN | disclosed |
| CN-107793399-A | CDK4/6 inhibitor and its preparation method and application | 上海翰森生物医药科技有限公司 | 2018-03-13 | — | — | CN | disclosed |