Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.41 |
| ▸ | HNF4A | P41235 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28204179 | 0.85 | TSHR (0.55) | TSHRALDH1A1HMGB1ALOX15FOLH1 | |
| SCHEMBL6935726 | 0.84 | TSHR (0.59) | TSHRALDH1A1HMGB1ALOX15FOLH1 | |
| SCHEMBL1245932 | 0.82 | TSHR (0.62) | TSHRALDH1A1HMGB1ALOX15FOLH1 | |
| SCHEMBL30452631 | 0.82 | TSHR (0.57) | TSHRALDH1A1HMGB1ALOX15FOLH1 | |
| SCHEMBL1246006 | 0.82 | TSHR (0.57) | TSHRALDH1A1HMGB1ALOX15FOLH1 | |
| SCHEMBL2896616 | 0.82 | PARP1 (0.44) | TSHRALDH1A1LMNAHPGDGAA | |
| SCHEMBL543047 | 0.82 | TSHR (0.45) | TSHRALDH1A1ALOX15TP53HTT | |
| SCHEMBL1614730 | 0.80 | TSHR (0.77) | TSHRALDH1A1HMGB1ALOX15NR4A1 | |
| SCHEMBL14831722 | 0.79 | HMGB1 (0.67) | TSHRALDH1A1HMGB1ALOX15FOLH1 | |
| SCHEMBL7642750 | 0.79 | TSHR (0.57) | TSHRALDH1A1ALOX15FOLH1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107820494-A | Nuclear receptor modulators | 艾伯维公司 | 2018-03-20 | — | — | CN | disclosed |