SCHEMBL1614730

SCHEMBL1614730

O=C(O)c1cccc(C(=O)O)c1Cl

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.77
ALDH1A1 P00352 4/20 0.61
ALOX15 P16050 1/20 0.60
HSD17B10 Q99714 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.52
LMNA P02545 1/20 0.52
NR4A1 P22736 2/20 0.50
KDM4E B2RXH2 2/20 0.50
HPGD P15428 2/20 0.50
NR4A2 P43354 1/20 0.50
NR4A3 Q92570 1/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
HMGB1 P09429 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
NAPRT Q6XQN6 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL21808814 0.97 TSHR (0.74) TSHRALDH1A1ALOX15HSD17B10SMN1; SMN2
Hydrochloric Acid SCHEMBL11483376 0.97 TSHR (0.74) TSHRALDH1A1ALOX15HSD17B10SMN1; SMN2
SCHEMBL19923193 0.87 TSHR (0.68) TSHRALDH1A1ALOX15HSD17B10SMN1; SMN2
SCHEMBL29904615 0.87 TSHR (1.00) TSHRALDH1A1ALOX15HSD17B10SMN1; SMN2
SCHEMBL97298 0.87 TSHR (1.00) TSHRALDH1A1ALOX15HSD17B10SMN1; SMN2
SCHEMBL8616119 0.85 TSHR (0.95) TSHRALDH1A1ALOX15HSD17B10SMN1; SMN2
SCHEMBL2048711 0.85 TSHR (0.95) TSHRALDH1A1ALOX15HSD17B10SMN1; SMN2
Hydrochloric Acid SCHEMBL11032955 0.85 TSHR (0.95) TSHRALDH1A1ALOX15HSD17B10SMN1; SMN2
SCHEMBL529909 0.85 TSHR (0.65) TSHRALDH1A1ALOX15HSD17B10SMN1; SMN2
SCHEMBL11800294 0.85 TSHR (0.95) TSHRALDH1A1ALOX15HSD17B10SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120040780-A Method for regulating and controlling luminescence of triphenylamine metal-organic framework material based on mixed ligand strategy 浙江大学 2025-05-27 CN claimed
US-10787569-B1 Process for preparing aerogels from polyamides UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 2020-09-29 US claimed
US-20100056750-A1 PROCESS FOR THE SYNTHESIS OF HALOGENATED AROMATIC DIACIDS E. I. DU PONT DE NEMOURS AND COMPANY 2010-03-04 US claimed
EP-2111388-A1 PROCESS FOR THE SYNTHESIS OF HALOGENATED AROMATIC DIACIDS E. I. Du Pont de Nemours and Company (US) 2009-10-28 EP claimed
WO-2008082501-A1 PROCESS FOR THE SYNTHESIS OF HALOGENATED AROMATIC DIACIDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-07-10 WO claimed
WO-2006063266-A2 ADDITIVE AND VEHICLE FOR INKS, PAINTS, COATINGS AND ADHESIVES OMNITECH ENVIRONMENTAL, LLC (US) 2006-06-15 WO claimed
US-20060128831-A1 Additive and vehicle for inks, paints, coatings and adhesives OMNITECH ENVIRONMENTAL, LLC 2006-06-15 US claimed
US-6420511-B1 SEPARATION AND PURIFICATION OF POLYESTERS COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2002-07-16 US claimed
US-5334699-A Polymeric initiator compounds XEROX CORPORATION (US) 1994-08-02 US claimed
US-5104618-A Mixture of chloro isophthalic acid derivative-2-(thiocyanomethyl thio) benzothiazole derivative and filler GUGLIELMO RICHARD J SR (US) 1992-04-14 US claimed
US-5082722-A Protective coating mixture of chloroisophthalic acid and derivative benzothiazole derivative GUGLIELMO RICHARD J SR (US) 1992-01-21 US claimed
US-12486279-B2 Indole alkaloid with fungicidal effect AZUL NATURAL S.A. DE C.V. (MX) 2025-12-02 US disclosed
CN-120040780-A Method for regulating and controlling luminescence of triphenylamine metal-organic framework material based on mixed ligand strategy 浙江大学 2025-05-27 CN disclosed
CN-119978421-A Chlorine modified metal organic framework material and preparation and application thereof 太原理工大学 2025-05-13 CN disclosed
CN-119159883-A Laminate, image display member, method for manufacturing image display member, mobile electronic device, and method for manufacturing mobile electronic device 日东电工株式会社 2024-12-20 CN disclosed
US-5104618-A Mixture of chloro isophthalic acid derivative-2-(thiocyanomethyl thio) benzothiazole derivative and filler GUGLIELMO RICHARD J SR (US) 1992-04-14 US disclosed
US-5082722-A Protective coating mixture of chloroisophthalic acid and derivative benzothiazole derivative GUGLIELMO RICHARD J SR (US) 1992-01-21 US disclosed
US-5082722-A Protective coating mixture of chloroisophthalic acid and derivative benzothiazole derivative GUGLIELMO RICHARD J SR (US) 1992-01-21 US disclosed
US-5036150-A Contain repeating unit derived from sterically hindered dihydroxy-diphenyl sulfone AMOCO CORPORATION (US) 1991-07-30 US disclosed
WO-1991010707-A1 IMPROVED PROCESS FOR FORMING POLY[CO(4-OXYBENZOATE/PARAPHENYLENEISOPHTHALATE)] AND RESULTING PRODUCT HOECHST CELANESE CORPORATION (US) 1991-07-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12486279-B2 Indole alkaloid with fungicidal effect IDO1, IDO2, INMT TSHR 3029/4885ALDH1A1 365/4885ALOX15 1906/4885
US-20100056750-A1 PROCESS FOR THE SYNTHESIS OF HALOGENATED AROMATIC DIACIDS TYR, DDC, DDT TSHR 2744/4885ALDH1A1 1407/4885ALOX15 2382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.