Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL962604 | 0.93 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2LMNAHTTCTSL | |
| SCHEMBL10702180 | 0.74 | GAA (0.46) | ALDH1A1SMN1; SMN2LMNAHTTNPSR1 | |
| SCHEMBL960634 | 0.73 | MAPT (0.61) | ALDH1A1SMN1; SMN2LMNAHTTRAB9A | |
| SCHEMBL14264702 | 0.73 | GAA (0.41) | ALDH1A1SMN1; SMN2LMNAHTTRAB9A | |
| SCHEMBL960636 | 0.73 | MAPT (0.61) | ALDH1A1SMN1; SMN2LMNAHTTRAB9A | |
| SCHEMBL12629713 | 0.72 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2LMNAHTTCTSL | |
| SCHEMBL4487426 | 0.71 | MEN1 (0.50) | ALDH1A1LMNACTSLCTSBRAB9A | |
| SCHEMBL8269193 | 0.71 | CA12 (0.41) | ALDH1A1SMN1; SMN2LMNAHTTRAB9A | |
| SCHEMBL4487424 | 0.71 | MEN1 (0.50) | ALDH1A1LMNACTSLCTSBRAB9A | |
| SCHEMBL12997974 | 0.71 | ATM (0.41) | ALDH1A1SMN1; SMN2LMNAHTTCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104662007-B | Cystathionine gamma lyase (CSE) inhibitor | 索瓦制药公司 | 2018-03-16 | — | — | CN | disclosed |