Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.53 |
| ▸ | RELA | Q04206 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL960634 | 1.00 | MAPT (0.61) | MAPTPOLBGAATDP1NPSR1 | |
| SCHEMBL16437840 | 0.87 | MAPT (0.56) | MAPTPOLBGAATDP1NPSR1 | |
| SCHEMBL24000933 | 0.79 | ALDH1A1 (0.44) | MAPTGAATDP1NPSR1ALDH1A1 | |
| SCHEMBL1563351 | 0.79 | RAB9A (0.81) | MAPTPOLBGAAALDH1A1LMNA | |
| SCHEMBL1563352 | 0.79 | RAB9A (0.81) | MAPTPOLBGAAALDH1A1LMNA | |
| SCHEMBL5732784 | 0.79 | RAB9A (0.81) | MAPTPOLBGAAALDH1A1LMNA | |
| SCHEMBL962604 | 0.78 | ALDH1A1 (0.48) | MAPTPOLBGAATDP1NPSR1 | |
| SCHEMBL3273659 | 0.77 | GAA (0.69) | MAPTPOLBGAATDP1NPSR1 | |
| SCHEMBL4413307 | 0.77 | GAA (0.69) | MAPTPOLBGAATDP1NPSR1 | |
| SCHEMBL13345208 | 0.77 | GAA (0.69) | MAPTPOLBGAATDP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247577-B2 | METHOD FOR THE REGIOSELECTIVE SYNTHESIS OF 1-ALKYL-3-HALOALKYL-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER IP GMBH (DE) | 2022-04-27 | — | — | EP | claimed |
| EP-2247577-B1 | METHOD FOR THE REGIOSELECTIVE SYNTHESIS OF 1-ALKYL-3-HALOALKYL-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER IP GMBH (DE) | 2015-12-23 | — | — | EP | claimed |
| CN-104277001-A | Method for the regioselective synthesis of 1-alkyl-3-haloalkyl-pyroazole-4-carboxylic acid derivatives | BAYER CROPSCIENCE AKTENGESELLSCHAFT | 2015-01-14 | — | — | CN | claimed |
| US-8629288-B2 | Method for the regioselective synthesis of 1-alky1-3-haloalkyl-pyrazole-4-carboxylic acid derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-14 | — | — | US | claimed |
| CN-102026981-A | Regioselective preparation of 1-alkyl-3-haloalkylpyrazole-4-carboxylic acid derivatives | BAYER CROPSCIENCE AKTENGESELLS | 2011-04-20 | — | — | CN | claimed |
| US-20110009642-A1 | Method for the Regioselective Synthesis of 1-Alkyl-3-haloalkyl-pyrazole-4-carboxylic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-01-13 | — | — | US | claimed |
| EP-2133341-A1 | Method for regioselective synthesis of 1-alkyl-3-haloalkyl-1-pyrazol-4-carbonic acid derivatives | Bayer CropScience AG (DE) | 2009-12-16 | — | — | EP | claimed |
| EP-0594671-B1 | COMPOSITION CONTAINING OLEFINICALLY UNSATURATED COMPOUNDS AND HYDRAZONES | HENKEL KGAA (DE) | 2000-09-20 | — | — | EP | claimed |
| US-6013750-A | CURABLE MIXTURE COMPRISING A HYDRAZONE INITIATOR, (METH)ACRYLIC ESTER MONOMERS, AND (METH)ACRYLATED POLYURETHANE HAVING POLYLACTONE, POLYESTER, AND/OR POLYETHER RESIDUES IN THE BACKBONE; BONDING STRENGTH, STABILITY | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2000-01-11 | — | — | US | claimed |
| EP-0594671-A1 | COMPOSITION CONTAINING OLEFINICALLY UNSATURATED COMPOUNDS AND HYDRAZONES | Henkel Kommanditgesellschaft auf Aktien (DE) | 1994-05-04 | — | — | EP | claimed |
| WO-1993001218-A1 | COMPOSITION CONTAINING OLEFINICALLY UNSATURATED COMPOUNDS AND HYDRAZONES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1993-01-21 | — | — | WO | claimed |
| US-4112146-A | Polyester resin compositions which are photocurable in the presence of oxygen and an organic hydrazone polymerization initiator | CELANESE CORPORATION (US) | 1978-09-05 | — | — | US | claimed |
| US-20230127728-A1 | MODIFIED GRAPHENE, METHOD OF PRODUCING MODIFIED GRAPHENE, MODIFIED GRAPHENE-RESIN COMPOSITE, MODIFIED GRAPHENE SHEET, AND MODIFIED GRAPHENE DISPERSION | CANON KK (JP) | 2023-04-27 | — | — | US | disclosed |
| EP-2247577-B2 | METHOD FOR THE REGIOSELECTIVE SYNTHESIS OF 1-ALKYL-3-HALOALKYL-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER IP GMBH (DE) | 2022-04-27 | — | — | EP | disclosed |
| EP-2247577-B1 | METHOD FOR THE REGIOSELECTIVE SYNTHESIS OF 1-ALKYL-3-HALOALKYL-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER IP GMBH (DE) | 2015-12-23 | — | — | EP | disclosed |
| CN-104277001-A | Method for the regioselective synthesis of 1-alkyl-3-haloalkyl-pyroazole-4-carboxylic acid derivatives | BAYER CROPSCIENCE AKTENGESELLSCHAFT | 2015-01-14 | — | — | CN | disclosed |
| WO-1995014720-A1 | AEROBIC ADHESIVE | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1995-06-01 | — | — | WO | disclosed |
| EP-0594671-A1 | COMPOSITION CONTAINING OLEFINICALLY UNSATURATED COMPOUNDS AND HYDRAZONES | Henkel Kommanditgesellschaft auf Aktien (DE) | 1994-05-04 | — | — | EP | disclosed |
| WO-1993001218-A1 | COMPOSITION CONTAINING OLEFINICALLY UNSATURATED COMPOUNDS AND HYDRAZONES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1993-01-21 | — | — | WO | disclosed |
| US-4000130-A | INDOLE DYES, POLYACRYLONITRILE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009642-A1 | Method for the Regioselective Synthesis of 1-Alkyl-3-haloalkyl-pyrazole-4-carboxylic Acid Derivatives | ATL3, HCAR3, AADAC | MAPT 4589/4885POLB 2448/4885GAA 1564/4885 |
| US-20230127728-A1 | MODIFIED GRAPHENE, METHOD OF PRODUCING MODIFIED GRAPHENE, MODIFIED GRAPHENE-RESIN COMPOSITE, MODIFIED GRAPHENE SHEET, AND MODIFIED GRAPHENE DISPERSION | GRIA1, GRIN1, NR3C1 | MAPT 3080/4885POLB 2219/4885GAA 2473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.