Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28203325 | 0.77 | CACNA1I (0.34) | KDM4ECACNA1ISCN9A | |
| SCHEMBL27540773 | 0.76 | EPHX2 (0.41) | SIRT1DDB1CRBNKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL28844174 | 0.74 | EPHX2 (0.40) | SIRT1DDB1CRBNKMT2ACYP2C19 | |
| Bromide SCHEMBL28875349 | 0.74 | EPHX2 (0.40) | SIRT1DDB1CRBNKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL18730111 | 0.74 | DDB1 (0.50) | SIRT1DDB1CRBNALDH1A1KMT2A | |
| SCHEMBL29128835 | 0.73 | MAPK1 (0.33) | ALDH1A1KMT2AMEN1LMNANPSR1 | |
| SCHEMBL30379200 | 0.73 | SIRT1 (0.44) | SIRT1DDB1CRBNALDH1A1KMT2A | |
| SCHEMBL30346054 | 0.72 | DRD2 (0.46) | ALDH1A1KMT2AMEN1LMNANPSR1 | |
| SCHEMBL3373919 | 0.72 | DRD2 (0.46) | ALDH1A1KMT2AMEN1LMNANPSR1 | |
| SCHEMBL29486049 | 0.72 | MAPT (0.38) | ALDH1A1KMT2AMEN1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107810185-A | Bicyclic heterocyclic derivatives as bromodomain inhibitors | 奥赖恩公司 | 2018-03-16 | — | — | CN | disclosed |