Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10290996 | 0.84 | FFAR4 (0.43) | FFAR4FFAR1MTNR1AMTNR1BAPP | |
| SCHEMBL23582812 | 0.83 | EPHX2 (0.46) | FFAR4FFAR1MTNR1AMTNR1BAPP | |
| SCHEMBL1094441 | 0.83 | MTNR1A (0.36) | FFAR4FFAR1MTNR1AMTNR1BAPP | |
| SCHEMBL12984627 | 0.81 | CYP4F2 (0.56) | FFAR4FFAR1APPCYP4F2CYP4A11 | |
| SCHEMBL1068886 | 0.80 | CYP4F2 (0.38) | MTNR1AMTNR1BAPPCYP4F2CYP4A11 | |
| SCHEMBL1128630 | 0.80 | CA2 (0.49) | AAK1 | |
| SCHEMBL23582768 | 0.80 | FFAR4 (0.44) | FFAR4MTNR1AMTNR1B | |
| SCHEMBL10982252 | 0.79 | CYP4F2 (0.50) | FFAR1MTNR1AMTNR1BCYP4F2CYP4A11 | |
| SCHEMBL16048629 | 0.79 | MTNR1A (0.40) | MTNR1AMTNR1BAPP | |
| SCHEMBL30927066 | 0.79 | NR3C2 (0.45) | FFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167921-A | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | 勃林格殷格翰动物保健美国公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-108699052-A | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | 梅里亚股份有限公司 | 2018-10-23 | — | — | CN | disclosed |
| CN-107835818-A | Anthelmintic depsipeptide compounds | 梅里亚股份有限公司 | 2018-03-23 | — | — | CN | disclosed |