Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 7/20 | 0.59 |
| ▸ | NOD2 | Q9HC29 | 5/20 | 0.59 |
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28414053 | 0.87 | NOD1 (0.61) | NOD1NOD2ALDH3A1ALOX5GAA | |
| SCHEMBL28228343 | 0.87 | CA12 (0.56) | NOD1NOD2ALDH3A1ALOX5CXCL8 | |
| SCHEMBL28145979 | 0.83 | NOD1 (0.57) | NOD1NOD2ALDH3A1ALOX5GAA | |
| SCHEMBL4060858 | 0.83 | NOD1 (0.59) | NOD1NOD2ALDH3A1ALOX5GAA | |
| SCHEMBL3902283 | 0.83 | ALDH3A1 (0.58) | NOD1NOD2ALDH3A1ALOX5GAA | |
| SCHEMBL27929447 | 0.83 | NOD1 (0.57) | NOD1NOD2ALDH3A1ALOX5GAA | |
| SCHEMBL30285319 | 0.83 | NOD1 (0.61) | NOD1NOD2ALDH3A1ALOX5GAA | |
| SCHEMBL29531344 | 0.83 | NOD1 (0.57) | NOD1NOD2ALDH3A1ALOX5GAA | |
| SCHEMBL26632851 | 0.83 | NOD1 (0.57) | NOD1NOD2ALDH3A1ALOX5GAA | |
| SCHEMBL28408604 | 0.82 | NOD1 (0.54) | NOD1NOD2ALDH3A1ALOX5GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109952295-A | A kind of CDK4/6 inhibitor and its preparation method and application | 江苏豪森药业集团有限公司 | 2019-06-28 | — | — | CN | disclosed |
| CN-109641868-A | Inhibitors of influenza viruses replication and its application method and purposes | 广东东阳光药业有限公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-108727369-A | Inhibitors of influenza viruses replication and application thereof | 广东东阳光药业有限公司 | 2018-11-02 | — | — | CN | disclosed |
| CN-108473477-A | The pyrimidine of aryl substitution for being used in influenza infection | 爱尔兰詹森科学公司 | 2018-08-31 | — | — | CN | disclosed |
| CN-108290869-A | HETEROCYCLIC INDOLES FOR USE IN INFLUENZA VIRUS INFECTION | 爱尔兰詹森科学公司 | 2018-07-17 | — | — | CN | disclosed |
| CN-107759571-A | Inhibitors of influenza viruses replication and its application method and purposes | 广东东阳光药业有限公司 | 2018-03-06 | — | — | CN | disclosed |
| CN-106573920-A | Indoles for use in influenza virus infection | 爱尔兰詹森科学公司 | 2017-04-19 | — | — | CN | disclosed |