Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTUD7B | Q6GQQ9 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | AKT2 | P31751 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1482815 | 0.82 | ALOX5AP (0.41) | OTUD7BKCNH2HRH3CHEK1AKT2 | |
| SCHEMBL2819756 | 0.78 | CHRM2 (0.33) | — | |
| SCHEMBL2820263 | 0.76 | SLC6A2 (0.31) | — | |
| Hydrochloric Acid SCHEMBL2823335 | 0.75 | SLC6A2 (0.30) | — | |
| SCHEMBL668390 | 0.74 | ACHE (0.36) | — | |
| SCHEMBL2820232 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL668528 | 0.72 | — | — | |
| SCHEMBL2819693 | 0.72 | SCD (0.37) | — | |
| SCHEMBL2819744 | 0.72 | — | — | |
| SCHEMBL2819737 | 0.71 | SCD (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1922320-B1 | DERIVATIVES OF 5-PYRIDAZINYL-1-AZABICYCLO[3.2.1]OCTANE, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | SANOFI AVENTIS (FR) | 2010-10-27 | — | — | EP | claimed |