SCHEMBL2820263

SCHEMBL2820263

Cc1cc(C)cc(-c2ccc(C34CCCN(CC3)C4)nn2)c1

nearest known ligand 0.49

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2823335 0.99 SLC6A2 (0.30) SLC6A2SLC6A4SLC6A3
SCHEMBL668390 0.83 ACHE (0.36)
SCHEMBL2819693 0.81 SCD (0.37)
SCHEMBL2818964 0.80 NPC1 (0.41)
SCHEMBL2819737 0.80 SCD (0.35)
SCHEMBL2822113 0.80 ALDH1A1 (0.43)
SCHEMBL2819756 0.80 CHRM2 (0.33)
SCHEMBL5221907 0.80 GRM5 (0.34)
SCHEMBL2846380 0.79 IL4I1 (0.38)
Hydrochloric Acid SCHEMBL2824030 0.79 NPC1 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1922320-B1 DERIVATIVES OF 5-PYRIDAZINYL-1-AZABICYCLO[3.2.1]OCTANE, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS SANOFI AVENTIS (FR) 2010-10-27 EP claimed