Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.50 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 4/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28857760 | 0.85 | TP53 (0.56) | MEN1KMT2AADORA2AADORA1TP53 | |
| SCHEMBL28008186 | 0.82 | MEN1 (0.51) | FABP4FABP5NLRP3MEN1KMT2A | |
| SCHEMBL28207152 | 0.80 | PTGER1 (0.47) | FABP4FABP5ADORA2AADORA1KDM4E | |
| SCHEMBL18152804 | 0.79 | FABP4 (0.50) | FABP4FABP5NLRP3MEN1KMT2A | |
| SCHEMBL14528675 | 0.77 | FABP4 (0.63) | FABP4FABP5MEN1KMT2AADORA1 | |
| SCHEMBL5198712 | 0.75 | TEK (0.48) | FABP4FABP5MEN1KMT2AKDM4E | |
| SCHEMBL11871844 | 0.74 | KDM4E (0.45) | FABP4FABP5NLRP3MEN1KMT2A | |
| SCHEMBL14528468 | 0.74 | FABP4 (0.66) | FABP4FABP5MEN1KMT2AADORA2A | |
| SCHEMBL18152846 | 0.74 | TSHR (0.61) | MEN1KMT2ATP53KDM4EALDH1A1 | |
| SCHEMBL8011287 | 0.73 | TEK (0.43) | FABP4FABP5MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026213-A | Imidazoles and glyoxaline cation with special alkaline stability | 康奈尔大学 | 2018-05-11 | — | — | CN | disclosed |