SCHEMBL28207236

SCHEMBL28207236

CCC(=O)Oc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1.[NaH]

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.52
CA1 P00915 2/20 0.52
VCAM1 P19320 10/20 0.49
RECQL P46063 2/20 0.46
LMNA P02545 1/20 0.46
HPN P05981 1/20 0.43
MAPT P10636 1/20 0.43
ALOX15 P16050 1/20 0.43
SIRT5 Q9NXA8 1/20 0.43
ALDH1A1 P00352 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
POLB P06746 1/20 0.42
TYR P14679 1/20 0.42
GAA P10253 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ESR1 P03372 1/20 0.42
KMT2A Q03164 1/20 0.42
HIF1A Q16665 1/20 0.42
GLRA3 O75311 1/20 0.42
GLRB P48167 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL100583 0.98 CA2 (0.53) CA2CA1VCAM1RECQLLMNA
Methane SCHEMBL4563808 0.97 CA2 (0.52) CA2CA1VCAM1RECQLLMNA
SCHEMBL30999666 0.97 CA2 (0.52) CA2CA1VCAM1RECQLLMNA
Ethylene SCHEMBL30811109 0.95 CA2 (0.50) CA2CA1VCAM1RECQLLMNA
Hydrazine SCHEMBL27936136 0.95 VCAM1 (0.51) CA2CA1VCAM1RECQLLMNA
Ethylene Glycol SCHEMBL3760959 0.93 VCAM1 (0.51) CA2CA1VCAM1RECQLLMNA
SCHEMBL27747898 0.91 CA2 (0.46) CA2CA1VCAM1RECQLLMNA
SCHEMBL28399977 0.91 VCAM1 (0.48) CA2CA1VCAM1RECQLLMNA
1,6-Hexanediol SCHEMBL1353108 0.89 VCAM1 (0.54) CA2CA1VCAM1RECQLLMNA
SCHEMBL29732475 0.89 CYP1A2 (0.47) CA2CA1VCAM1RECQLLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107827921-A A kind of Hinered phenols antioxidant of novel siliceous and preparation method thereof 山东三丰新材料有限公司 2018-03-23 CN disclosed