Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27786320 | 1.00 | KDM4E (0.58) | KDM4EADRB2ALDH1A1SMN1; SMN2HTR7 | |
| SCHEMBL28857495 | 0.94 | KDM4E (0.60) | KDM4EADRB2ALDH1A1SMN1; SMN2HTR7 | |
| SCHEMBL13739869 | 0.92 | ADRB2 (0.61) | KDM4EADRB2ALDH1A1SMN1; SMN2HTR7 | |
| SCHEMBL9715200 | 0.92 | ADRB2 (0.61) | KDM4EADRB2ALDH1A1SMN1; SMN2HTR7 | |
| SCHEMBL27630456 | 0.92 | ADRB2 (0.61) | KDM4EADRB2ALDH1A1SMN1; SMN2HTR7 | |
| SCHEMBL5969665 | 0.92 | ADRB2 (0.61) | KDM4EADRB2ALDH1A1SMN1; SMN2HTR7 | |
| SCHEMBL10434829 | 0.92 | ADRB2 (0.61) | KDM4EADRB2ALDH1A1SMN1; SMN2HTR7 | |
| SCHEMBL13739675 | 0.92 | ADRB2 (0.61) | KDM4EADRB2ALDH1A1SMN1; SMN2HTR7 | |
| SCHEMBL3826240 | 0.92 | ADRB2 (0.61) | KDM4EADRB2ALDH1A1SMN1; SMN2HTR7 | |
| SCHEMBL13739368 | 0.92 | ADRB2 (0.61) | KDM4EADRB2ALDH1A1SMN1; SMN2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107842706-A | A kind of break-in method of coefficient of friction between reduction metallic rubbing pairs | 齐鲁工业大学 | 2018-03-27 | — | — | CN | claimed |
| CN-107842706-A | A kind of break-in method of coefficient of friction between reduction metallic rubbing pairs | 齐鲁工业大学 | 2018-03-27 | — | — | CN | disclosed |