Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29700330 | 0.82 | CYP2A6 (0.47) | L3MBTL1ALDH1A1HSD17B10KMT2AMEN1 | |
| SCHEMBL428529 | 0.82 | CYP2A6 (0.47) | L3MBTL1ALDH1A1HSD17B10KMT2AMEN1 | |
| SCHEMBL27612022 | 0.76 | MAOB (0.49) | ALDH1A1HSD17B10KMT2AMEN1MAPT | |
| SCHEMBL4957626 | 0.76 | HPGD (0.83) | HPGDALOX12L3MBTL1KIF11GSK3B | |
| SCHEMBL395942 | 0.76 | HPGD (0.83) | HPGDALOX12L3MBTL1KIF11GSK3B | |
| SCHEMBL18289622 | 0.76 | HPGD (0.83) | HPGDALOX12L3MBTL1KIF11GSK3B | |
| SCHEMBL18289621 | 0.76 | HPGD (0.83) | HPGDALOX12L3MBTL1KIF11GSK3B | |
| Butane SCHEMBL5333879 | 0.75 | CA12 (0.44) | ALDH1A1MAPTKDM4ETDP1RAB9A | |
| SCHEMBL30436163 | 0.74 | HPGD (0.68) | HPGDALOX12L3MBTL1KIF11ALDH1A1 | |
| SCHEMBL20049529 | 0.73 | HPGD (0.78) | HPGDALOX12L3MBTL1KIF11PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107805255-A | Furans [3,2 b] pyridine 2 (1H) ketone compounds, preparation method and medical usage | 中国药科大学 | 2018-03-16 | — | — | CN | disclosed |