Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL428529 | 1.00 | CYP2A6 (0.47) | CYP2A6MAOBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27612022 | 0.93 | MAOB (0.49) | CYP2A6MAOBRAB9ANPC1SMN1; SMN2 | |
| Butane SCHEMBL5333879 | 0.92 | CA12 (0.44) | CYP2A6MAOBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5329937 | 0.89 | RAB9A (0.43) | CYP2A6MAOBRAB9ANPC1SMN1; SMN2 | |
| Propionic Acid SCHEMBL27841948 | 0.86 | MAOA (0.47) | MAOBRAB9ANPC1SMN1; SMN2MAOA | |
| SCHEMBL3799970 | 0.85 | MAPT (0.46) | CYP2A6RAB9ANPC1SMN1; SMN2MAOA | |
| SCHEMBL30469300 | 0.83 | DYRK1A (0.49) | MAOBRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL20557631 | 0.83 | DYRK1A (0.49) | MAOBRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| Ethoxycarbonyl Group SCHEMBL27813205 | 0.83 | CYP2A6 (0.41) | CYP2A6MAOBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28207356 | 0.82 | HPGD (0.51) | RAB9ASMN1; SMN2ALDH1A1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4031243-A1 | GLUE DEGRADERS AND METHODS OF USE THEREOF | Novartis AG (CH) | 2022-07-27 | — | — | EP | disclosed |