Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29700330 | 1.00 | CYP2A6 (0.47) | CYP2A6MAOBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27612022 | 0.93 | MAOB (0.49) | CYP2A6MAOBRAB9ANPC1SMN1; SMN2 | |
| Butane SCHEMBL5333879 | 0.92 | CA12 (0.44) | CYP2A6MAOBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5329937 | 0.89 | RAB9A (0.43) | CYP2A6MAOBRAB9ANPC1SMN1; SMN2 | |
| Propionic Acid SCHEMBL27841948 | 0.86 | MAOA (0.47) | MAOBRAB9ANPC1SMN1; SMN2MAOA | |
| SCHEMBL3799970 | 0.85 | MAPT (0.46) | CYP2A6RAB9ANPC1SMN1; SMN2MAOA | |
| SCHEMBL30469300 | 0.83 | DYRK1A (0.49) | MAOBRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL20557631 | 0.83 | DYRK1A (0.49) | MAOBRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| Ethoxycarbonyl Group SCHEMBL27813205 | 0.83 | CYP2A6 (0.41) | CYP2A6MAOBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28207356 | 0.82 | HPGD (0.51) | RAB9ASMN1; SMN2ALDH1A1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108484548-A | A kind of preparation method of 5- nitro-benzofurans -2- formic ether compounds | 扬州工业职业技术学院 | 2018-09-04 | — | — | CN | claimed |
| US-9499507-B2 | Method for preparing 5-amino-benzoyl-benzofuran derivatives | SANOFI (FR) | 2016-11-22 | — | — | US | claimed |
| US-20150031901-A1 | METHOD FOR PREPARING 5-AMINO-BENZOFURAN DERIVATIVES | SANOFI (FR) | 2015-01-29 | — | — | US | claimed |
| CN-102659726-B | Method for synthesis of dronedarone | FUJIAN COSUNTER PHARMACEUTICAL CO LTD | 2014-11-19 | — | — | CN | claimed |
| US-8884033-B2 | Process for preparing aminobenzoylbenzofuran derivatives | SANOFI (FR) | 2014-11-11 | — | — | US | claimed |
| US-20130165675-A1 | PROCESS FOR PREPARING AMINOBENZOYLBENZOFURAN DERIVATIVES | SANOFI (FR) | 2013-06-27 | — | — | US | claimed |
| WO-2013079866-A1 | METHOD FOR PREPARING 5-AMINO-BENZOYL-BENZOFURAN DERIVATIVES | SANOFI (FR) | 2013-06-06 | — | — | WO | claimed |
| EP-2595976-A1 | PROCESS FOR PREPARING AMINOBENZOYLBENZOFURAN DERIVATIVES | SANOFI (FR) | 2013-05-29 | — | — | EP | claimed |
| CN-103108869-A | Process for preparing aminobenzoylbenzofuran derivatives | SANOFI SA | 2013-05-15 | — | — | CN | claimed |
| WO-2012010788-A1 | PROCESS FOR PREPARING AMINOBENZOYLBENZOFURAN DERIVATIVES | SANOFI (FR) | 2012-01-26 | — | — | WO | claimed |
| WO-2008139057-A2 | METHOD FOR PREPARING 2-(N-BUTYL)-3-(4-HYDROXYBENZOYL)-5-NITROBENZOFURANE | FINORGA (FR) | 2008-11-20 | — | — | WO | claimed |
| CN-114401960-B | Glue degradation agent and using method thereof | NOVARTIS AG (CH) | 2026-05-26 | — | — | CN | disclosed |
| CN-115594602-B | Method for synthesizing aromatic amine by visible light induction | 南京大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-114380730-B | Method for synthesizing N-aryl pyrrole and N-aryl indole by denitration coupling of nitroarene | 广西大学 | 2023-12-05 | — | — | CN | disclosed |
| CN-115594602-A | Visible light induced method for synthesizing aromatic amine | 南京大学（CN） | 2023-01-13 | — | — | CN | disclosed |
| EP-0652214-A1 | N-Aryl-2-cyano-3-hydroxy propenamide derivatives, a method for their preparation, their use as medicaments and pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1995-05-10 | — | — | EP | disclosed |
| WO-1994014801-A1 | HETEROCYCLIC UREA DERIVATIVES AS 5HT2C AND 5HT2B ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-07-07 | — | — | WO | disclosed |
| WO-1994013620-A1 | AMINOMETHYLINDANS, -BENZOFURANES AND -BENZOTHIOPHENES | H. LUNDBECK A/S (DK) | 1994-06-23 | — | — | WO | disclosed |
| US-5223510-A | ALKYLAMINOALKYL DERIVATIVES OF BENZOFURAN, BENZOTHIOPHENE, INDOLE AND INDOLIZINE, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SANOFI (FR) | 1993-06-29 | — | — | US | disclosed |
| US-3963717-A | ANTIINFLAMMATORY, ANALGESIC | SANDOZ, INC. (US) | 1976-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165675-A1 | PROCESS FOR PREPARING AMINOBENZOYLBENZOFURAN DERIVATIVES | ALKBH5, ALKBH1, PRMT5 | CYP2A6 345/4885MAOB 24/4885RAB9A 1329/4885 |
| US-20150031901-A1 | METHOD FOR PREPARING 5-AMINO-BENZOFURAN DERIVATIVES | ALKBH5, CYP3A5, ALKBH1 | CYP2A6 235/4885MAOB 440/4885RAB9A 3549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.