Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | PARP1 | P09874 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1871761 | 0.88 | ALDH1A1 (0.68) | ALDH1A1TDP1KMT2AL3MBTL1MAPK1 | |
| SCHEMBL111605 | 0.88 | ALDH1A1 (0.68) | ALDH1A1TDP1KMT2AL3MBTL1MAPK1 | |
| Hydrochloric Acid SCHEMBL27438937 | 0.86 | ALDH1A1 (0.66) | ALDH1A1TDP1KMT2AL3MBTL1MAPK1 | |
| SCHEMBL27168266 | 0.86 | ALDH1A1 (0.66) | ALDH1A1TDP1KMT2AL3MBTL1MAPK1 | |
| Ammonia Solution, Strong SCHEMBL3117410 | 0.86 | ALDH1A1 (0.66) | ALDH1A1TDP1KMT2AL3MBTL1MAPK1 | |
| Benzamide SCHEMBL28875161 | 0.85 | MAPT (0.57) | PARP10ALDH1A1TDP1KMT2AL3MBTL1 | |
| Propionic Acid SCHEMBL18954211 | 0.84 | ALDH1A1 (0.63) | ALDH1A1TDP1KMT2AL3MBTL1MAPK1 | |
| Formaldehyde SCHEMBL28008518 | 0.84 | ALDH1A1 (0.63) | ALDH1A1TDP1KMT2AL3MBTL1MAPK1 | |
| SCHEMBL27341710 | 0.83 | ALDH1A1 (0.61) | ALDH1A1TDP1KMT2AL3MBTL1MAPK1 | |
| SCHEMBL27567162 | 0.83 | ALDH1A1 (0.61) | ALDH1A1TDP1KMT2AL3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026028-A | Treatment of diabetes and metabolic syndrome with novel dual modulators of soluble epoxide hydrolase and peroxisome proliferator-activated receptors | 威斯康星州医药大学股份有限公司 | 2018-05-11 | — | — | CN | disclosed |