Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | PARP1 | P09874 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzamide SCHEMBL28224034 | 0.86 | MAPT (0.53) | MAPTPOLBCYP3A4PARP1TSHR | |
| Benzamide SCHEMBL28207640 | 0.85 | PARP10 (0.55) | MAPTPOLBCYP3A4PARP1TSHR | |
| Benzamide SCHEMBL28308326 | 0.84 | PARP1 (0.59) | MAPTPOLBCYP3A4PARP1TSHR | |
| Benzamide SCHEMBL27654010 | 0.84 | MAPT (0.59) | MAPTPOLBCYP3A4PARP1TSHR | |
| Thiobenzoic Acid SCHEMBL3749735 | 0.82 | ALDH1A1 (0.47) | MAPTTSHRMEN1KMT2AALDH1A1 | |
| Benzamide SCHEMBL27276187 | 0.82 | MAPT (0.57) | MAPTPOLBCYP3A4PARP1TSHR | |
| Ethyl Propionate SCHEMBL27396332 | 0.81 | LMNA (0.52) | CYP3A4TSHRHSD17B10MEN1KMT2A | |
| Benzamide SCHEMBL4408659 | 0.81 | PARP1 (0.67) | MAPTPOLBCYP3A4PARP1TSHR | |
| Benzamide SCHEMBL28263471 | 0.81 | PARP1 (0.67) | MAPTPOLBCYP3A4PARP1TSHR | |
| Ethyl Propionate SCHEMBL27658259 | 0.81 | MEN1 (0.52) | MAPTTSHRMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110072858-A | Indole derivatives as glucagon receptor antagonist | 詹森药业有限公司 | 2019-07-30 | — | — | CN | disclosed |