Formic Acid

Formic Acid

SCHEMBL28207672

Nc1c(Cl)cccc1Cl.O=CO

nearest known ligand 0.48

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
TSHR P16473 4/20 0.40
NR4A2 P43354 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2A6 P11509 1/20 0.38
HAVCR2 Q8TDQ0 1/20 0.37
AKR1B1 P15121 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
LMNA P02545 1/20 0.36
SLC22A1 O15245 1/20 0.36
HTR1A P08908 1/20 0.36
ADRA2A P08913 1/20 0.36
CHRM1 P11229 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36
MAOA P21397 1/20 0.36
DRD1 P21728 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL71630 0.84
Hydrochloric Acid SCHEMBL29274502 0.81 TSHR (0.50) ALDH1A1MEN1KMT2ATDP1TSHR
SCHEMBL3804192 0.81 TSHR (0.50) ALDH1A1MEN1KMT2ATDP1TSHR
SCHEMBL9055171 0.78 ALDH1A1 (0.42) ALDH1A1MEN1KMT2ATDP1TSHR
SCHEMBL23702718 0.77 TSHR (0.42) ALDH1A1MEN1KMT2ATDP1TSHR
SCHEMBL28389450 0.77 CA1 (0.44) ALDH1A1MEN1KMT2ATDP1TSHR
SCHEMBL1313885 0.76 ALDH1A1 (0.50) ALDH1A1MEN1KMT2ATDP1TSHR
SCHEMBL30106730 0.76 ALDH1A1 (0.50) ALDH1A1MEN1KMT2ATDP1TSHR
1,2-Dichlorobenzene SCHEMBL28852872 0.76 TSHR (0.59) ALDH1A1MEN1KMT2ATDP1TSHR
Formic Acid SCHEMBL29776200 0.75 ALDH1A1 (0.43) ALDH1A1MEN1KMT2ATDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105542584-B A kind of thermal sensation fluorine carbon functional paint and preparation method containing azobenzene/carbon hybrid material 天津大学 2018-04-03 CN disclosed