Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TET2 | Q6N021 | 5/20 | 0.47 |
| ▸ | ACLY | P53396 | 2/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.36 |
| ▸ | TET3 | O43151 | 1/20 | 0.33 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Itaconate SCHEMBL286967 | 0.84 | ALOX15 (0.75) | ALOX15HSD17B10TET2LDHASRR | |
| Itaconate SCHEMBL21523 | 0.84 | — | — | |
| Itaconate SCHEMBL29886131 | 0.84 | — | — | |
| Itaconate SCHEMBL4599739 | 0.82 | ALOX15 (0.65) | ALOX15HSD17B10TET2LDHASRR | |
| Itaconate SCHEMBL4599744 | 0.82 | ALOX15 (0.65) | ALOX15HSD17B10TET2LDHASRR | |
| Itaconate SCHEMBL4307310 | 0.82 | ALOX15 (0.54) | ALOX15HSD17B10TET2ACLYLDHA | |
| Itaconate SCHEMBL1888723 | 0.82 | ALOX15 (0.71) | ALOX15HSD17B10TET2LDHASRR | |
| Itaconate SCHEMBL18554417 | 0.82 | ALOX15 (0.71) | ALOX15HSD17B10TET2LDHASRR | |
| Itaconate SCHEMBL2397428 | 0.82 | ALOX15 (0.71) | ALOX15HSD17B10TET2LDHASRR | |
| Itaconate SCHEMBL7518254 | 0.82 | ALOX15 (0.71) | ALOX15HSD17B10TET2LDHASRR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104704067-B | Smooth self-lubricating polymer surface | 哈佛学院院长及董事 | 2018-04-10 | — | — | CN | disclosed |