Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TET2 | Q6N021 | 5/20 | 0.39 |
| ▸ | TET3 | O43151 | 1/20 | 0.35 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Itaconate SCHEMBL28208332 | 0.82 | ALOX15 (0.58) | ALOX15HSD17B10TET2TET3TET1 | |
| Itaconate SCHEMBL286967 | 0.81 | ALOX15 (0.75) | ALOX15HSD17B10TET2TET3TET1 | |
| Itaconate SCHEMBL29886131 | 0.81 | — | — | |
| Itaconate SCHEMBL21523 | 0.81 | — | — | |
| Itaconate SCHEMBL4599739 | 0.79 | ALOX15 (0.65) | ALOX15HSD17B10TET2TET3TET1 | |
| Itaconate SCHEMBL28352485 | 0.79 | ALOX15 (0.65) | ALOX15HSD17B10TET2TET3TET1 | |
| Itaconate SCHEMBL4599744 | 0.79 | ALOX15 (0.65) | ALOX15HSD17B10TET2TET3TET1 | |
| Itaconate SCHEMBL9244093 | 0.78 | ALOX15 (0.71) | ALOX15HSD17B10TET2TET3TET1 | |
| Itaconate SCHEMBL2397428 | 0.78 | ALOX15 (0.71) | ALOX15HSD17B10TET2TET3TET1 | |
| Itaconate SCHEMBL6552810 | 0.78 | ALOX15 (0.71) | ALOX15HSD17B10TET2TET3TET1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090012250-A1 | NOVEL POLYMERIZABLE SURFACE ACTIVE MONOMERS WITH BOTH FLUORINE-CONTAINING GROUPS AND HYDROPHILIC GROUPS | BAUSCH & LOMB INCORPORATED | 2009-01-08 | — | — | US | disclosed |
| WO-2009005954-A2 | NOVEL POLYMERIZABLE SURFACE ACTIVE MONOMERS WITH BOTH FLUORINE-CONTAINING GROUPS AND HYDROPHILIC GROUPS | BAUSCH & LOMB INCORPORATED (US) | 2009-01-08 | — | — | WO | disclosed |
| US-20030162853-A1 | Use of adsorbent polymer particles in DNA separation | PROMETIC BIOSCIENCES LTD. (GB) | 2003-08-28 | — | — | US | disclosed |