SCHEMBL28208697

SCHEMBL28208697

CCCN1CCOCC1.F[B-](F)(F)F

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
KDM4E B2RXH2 3/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
KEAP1 Q14145 1/20 0.45
MAPK1 P28482 2/20 0.44
SIGMAR1 Q99720 2/20 0.44
CYP1A2 P05177 1/20 0.44
CHRM2 P08172 1/20 0.44
CHRM1 P11229 1/20 0.44
HTR2A P28223 1/20 0.44
SCN1A P35498 1/20 0.44
HTR2B P41595 1/20 0.44
KCNH2 Q12809 1/20 0.44
SCN2A Q99250 1/20 0.44
SCN3A Q9NY46 1/20 0.44
HRH3 Q9Y5N1 1/20 0.44
USP2 O75604 1/20 0.43
LMNA P02545 1/20 0.43
GLA P06280 1/20 0.41
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33271 0.91
Ammonia Solution, Strong SCHEMBL388879 0.88 ALDH1A1 (0.50) ALDH1A1KDM4ESMN1; SMN2KEAP1MAPK1
Bromide SCHEMBL2812026 0.88 ALDH1A1 (0.50) ALDH1A1KDM4ESMN1; SMN2KEAP1MAPK1
Water SCHEMBL28087307 0.88 ALDH1A1 (0.50) ALDH1A1KDM4ESMN1; SMN2KEAP1MAPK1
SCHEMBL19478722 0.88 ALDH1A1 (0.56) ALDH1A1KDM4ESMN1; SMN2KEAP1MAPK1
SCHEMBL31474386 0.88 ALDH1A1 (0.50) ALDH1A1KDM4ESMN1; SMN2KEAP1MAPK1
Hydrochloric Acid SCHEMBL8005745 0.88 MAPK1 (0.52) ALDH1A1KDM4ESMN1; SMN2KEAP1MAPK1
SCHEMBL12386148 0.88 ALDH1A1 (0.56) ALDH1A1KDM4ESMN1; SMN2KEAP1MAPK1
Iodide SCHEMBL8208149 0.88 ALDH1A1 (0.50) ALDH1A1KDM4ESMN1; SMN2KEAP1MAPK1
Hydrogen Sulfide SCHEMBL28301039 0.88 ALDH1A1 (0.50) ALDH1A1KDM4ESMN1; SMN2KEAP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105218688-B A kind of starch flocculant of polyamine cationic polymer modification and preparation method thereof 黄河水利职业技术学院 2018-04-10 CN disclosed