Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 4/20 | 0.35 |
| ▸ | ALPL | P05186 | 8/20 | 0.34 |
| ▸ | TACR3 | P29371 | 2/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | TACR2 | P21452 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13779967 | 0.80 | ALPL (0.52) | ALPL | |
| SCHEMBL14925554 | 0.79 | ALPL (0.51) | ALPLTACR3KMT2A | |
| SCHEMBL16812287 | 0.78 | NPC1 (0.44) | KDM5AMEN1KMT2AKDM5B | |
| SCHEMBL18161035 | 0.77 | KDM5A (0.44) | KDM5AALPLKDM5B | |
| SCHEMBL17672418 | 0.75 | KDM5A (0.45) | KDM5AKDM5B | |
| SCHEMBL14484511 | 0.74 | KDM5A (0.39) | KDM5AMEN1KMT2AKDM5B | |
| SCHEMBL16564670 | 0.74 | CYP3A4 (0.40) | ALPL | |
| SCHEMBL15258531 | 0.74 | KDM4E (0.51) | TACR3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL17672405 | 0.74 | KDM5A (0.44) | KDM5AKDM5B | |
| SCHEMBL28208763 | 0.73 | KDM5A (0.43) | KDM5AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107912040-A | Pyrrolidine Amide Compounds As Histone Demethylase Inhibitors | 基因泰克公司 | 2018-04-13 | — | — | CN | disclosed |