Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27914603 | 0.84 | NR4A3 (0.44) | POLBNR4A3MAPK1ALDH1A1KDM4E | |
| SCHEMBL433371 | 0.79 | POLB (1.00) | POLBMAPK1RIPK2ALDH1A1KDM4E | |
| SCHEMBL7826898 | 0.75 | POLB (0.59) | POLBHPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL28840375 | 0.74 | LMNA (0.46) | MAPK1ALDH1A1KDM4ECYP2C9MAPT | |
| Hydrazine SCHEMBL28166056 | 0.72 | TSHR (0.57) | POLBNR4A3HPGDALDH1A1KDM4E | |
| Benzene SCHEMBL27265959 | 0.72 | TSHR (0.61) | POLBNR4A3HPGDALDH1A1KDM4E | |
| SCHEMBL27703149 | 0.72 | TSHR (0.61) | POLBNR4A3HPGDALDH1A1KDM4E | |
| SCHEMBL756585 | 0.72 | TSHR (0.61) | POLBNR4A3HPGDALDH1A1KDM4E | |
| Oxirane SCHEMBL27573676 | 0.70 | TSHR (0.52) | POLBNR4A3HPGDALDH1A1KDM4E | |
| SCHEMBL15428751 | 0.70 | POLB (0.61) | POLBRIPK2ALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105585583-B | A kind of non-peptides apoptosis inhibitory protein antagonist and its synthetic method and application | 广东工业大学 | 2018-04-13 | — | — | CN | disclosed |