Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28083786 | 0.94 | LMNA (0.42) | LMNAHDAC4ELANENOTUMKDM4E | |
| SCHEMBL15524867 | 0.83 | MYC (0.45) | LMNAELANEKDM4EALDH1A1MAPK1 | |
| Bicarbonate SCHEMBL10672835 | 0.82 | NOTUM (0.57) | LMNAHDAC4NOTUMKDM4EALDH1A1 | |
| SCHEMBL27605945 | 0.79 | LMNA (0.47) | LMNAHDAC4ELANEALDH1A1KAT6A | |
| SCHEMBL28036425 | 0.78 | HDAC4 (0.43) | LMNAHDAC4ELANENOTUMKDM4E | |
| SCHEMBL27250 | 0.78 | NOTUM (0.65) | LMNAHDAC4NOTUMKDM4EALDH1A1 | |
| SCHEMBL27584512 | 0.78 | LMNA (0.48) | LMNAHDAC4NOTUMKDM4EALDH1A1 | |
| SCHEMBL28803951 | 0.77 | LMNA (0.42) | LMNAHDAC4ELANENOTUMKDM4E | |
| SCHEMBL1586230 | 0.77 | ELANE (0.49) | LMNAELANEKDM4EALDH1A1KAT6A | |
| Formaldehyde SCHEMBL27652263 | 0.76 | NOTUM (0.59) | LMNAHDAC4NOTUMKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107072923-A | Hair colouring layer, method and kit therefor | 诺赛尔股份有限公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-107072920-A | Hair coloring layer, method and its external member | 诺赛尔股份有限公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-106432082-A | Preparation method of edaravone impurity standard product | 合肥久诺医药科技有限公司 | 2017-02-22 | — | — | CN | disclosed |