Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL28209129

CCOC(C)=O.CO.O=C(O)C(F)(F)F.O=S(=O)(O)O

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Trifluoroacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.54
HSD17B10 Q99714 2/20 0.54
LMNA P02545 1/20 0.54
TSHR P16473 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
KMT2A Q03164 2/20 0.34
HTT P42858 2/20 0.34
MEN1 O00255 1/20 0.34
HDAC4 P56524 2/20 0.33
HDAC6 Q9UBN7 2/20 0.33
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
ALOX15 P16050 1/20 0.32
MGAM O43451 1/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
SOAT1 P35610 1/20 0.32
CES2 O00748 3/20 0.32
ACHE P22303 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL1517904 0.90 ALDH1A1 (0.67) ALDH1A1HSD17B10LMNATSHRHDAC4
Trifluoroacetic Acid SCHEMBL28645679 0.88 ALDH1A1 (0.64) ALDH1A1HSD17B10LMNATSHRKMT2A
Ethyl Acetate SCHEMBL9007287 0.83 ALDH1A1 (0.70) ALDH1A1HSD17B10LMNATSHRALOX15
Ethyl Acetate SCHEMBL10994135 0.83 ALDH1A1 (0.78) ALDH1A1HSD17B10LMNATSHRALOX15
Ethyl Acetate SCHEMBL5590823 0.83 ALDH1A1 (0.78) ALDH1A1HSD17B10LMNATSHRALOX15
Trifluoroacetic Acid SCHEMBL28225221 0.82 ALDH1A1 (0.56) ALDH1A1HSD17B10LMNAL3MBTL1KMT2A
Ethyl Acetate SCHEMBL28062101 0.81 ALDH1A1 (0.74) ALDH1A1HSD17B10LMNATSHRALOX15
Ethyl Acetate SCHEMBL7010595 0.81 ALDH1A1 (0.74) ALDH1A1HSD17B10LMNATSHRALOX15
Ethyl Acetate SCHEMBL28062099 0.81 ALDH1A1 (0.74) ALDH1A1HSD17B10LMNATSHRALOX15
Trifluoroacetic Acid SCHEMBL27515981 0.80 ALDH1A1 (0.48) ALDH1A1HSD17B10LMNATSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107782821-B Analysis method of neuromuscular blocking agent 四川科瑞德制药股份有限公司 2021-11-09 CN disclosed
CN-107782821-A A kind of analysis method of neuromuscular blocking agent 四川科瑞德制药股份有限公司 2018-03-09 CN disclosed