Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 10/20 | 0.83 |
| ▸ | FABP3 | P05413 | 9/20 | 0.83 |
| ▸ | FABP5 | Q01469 | 9/20 | 0.83 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.80 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14916322 | 0.91 | FABP4 (1.00) | FABP4FABP3FABP5NPSR1CYP2C9 | |
| SCHEMBL14917289 | 0.90 | FABP4 (0.98) | FABP4FABP3FABP5NPSR1CYP2C9 | |
| SCHEMBL2822705 | 0.87 | ALDH1A1 (0.64) | FABP4FABP3FABP5NPSR1CYP2C9 | |
| SCHEMBL18231466 | 0.86 | FABP4 (0.79) | FABP4FABP3FABP5NPSR1CYP2C9 | |
| SCHEMBL14916686 | 0.86 | FABP4 (0.78) | FABP4FABP3FABP5NPSR1CYP2C9 | |
| SCHEMBL14932771 | 0.86 | FABP4 (0.71) | FABP4FABP3FABP5NPSR1CYP2C9 | |
| SCHEMBL14917037 | 0.86 | FABP3 (0.74) | FABP4FABP3FABP5NPSR1CYP2C9 | |
| SCHEMBL18231455 | 0.85 | FABP4 (0.77) | FABP4FABP3FABP5NPSR1CYP2C9 | |
| SCHEMBL14916460 | 0.84 | FABP4 (0.87) | FABP4FABP3FABP5NPSR1CYP2C9 | |
| SCHEMBL14916337 | 0.84 | FABP3 (0.72) | FABP4FABP3FABP5NPSR1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809605-B1 | QUINOLINES AS ALLOSTERIC ENHANCERS OF THE GABA-B RECEPTORS | HOFFMANN LA ROCHE (CH) | 2010-08-11 | — | — | EP | claimed |