Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | SLC5A2 | P31639 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAPDH | P04406 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5888997 | 0.98 | CCNE1 (0.43) | ALDH1A1FDPSCCNE1CDK2CDK5 | |
| SCHEMBL23430695 | 0.87 | CCNE1 (0.42) | ALDH1A1FDPSCCNE1CDK2CDK5 | |
| SCHEMBL2820595 | 0.86 | FDPS (0.45) | ALDH1A1FDPSCCNE1CDK2CDK5 | |
| SCHEMBL18067938 | 0.86 | ALDH1A1 (0.39) | ALDH1A1FDPSCCNE1CDK2CDK5 | |
| SCHEMBL21199684 | 0.85 | ALDH1A1 (0.40) | ALDH1A1FDPSCCNE1CDK2CDK5 | |
| SCHEMBL21199725 | 0.85 | CCNE1 (0.44) | ALDH1A1FDPSCCNE1CDK2CDK5 | |
| SCHEMBL11724812 | 0.84 | ALDH1A1 (0.42) | ALDH1A1CCNE1CDK2CDK5SLC5A2 | |
| SCHEMBL13447373 | 0.83 | FDPS (0.40) | ALDH1A1FDPSCCNE1CDK2CDK5 | |
| SCHEMBL27779049 | 0.83 | FDPS (0.37) | ALDH1A1FDPSCCNE1CDK2CDK5 | |
| SCHEMBL13325277 | 0.82 | SPHK1 (0.40) | ALDH1A1FDPSCCNE1CDK2CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240890-A1 | Novel benzamidine derivatives, process for the preparation thereof and pharmaceutical composition comprising the same | DONG WHA PHARMACEUTICAL IND. CO., LTD. | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240890-A1 | Novel benzamidine derivatives, process for the preparation thereof and pharmaceutical composition comprising the same | CMA1, IL5, HRH4 | ALDH1A1 1751/4885FDPS 1669/4885CCNE1 3326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.