Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F12 | P00748 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | FURIN | P09958 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | F10 | P00742 | 3/20 | 0.41 |
| ▸ | PLAU | P00749 | 3/20 | 0.41 |
| ▸ | PLAT | P00750 | 3/20 | 0.41 |
| ▸ | PLG | P00747 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.39 |
| ▸ | ESR1 | P03372 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7333075 | 0.89 | F2 (0.41) | F12LMNAPRSS1PRSS2PRSS3 | |
| SCHEMBL28171884 | 0.83 | PRSS1 (0.47) | F12LMNAPRSS1PRSS2PRSS3 | |
| SCHEMBL2107802 | 0.80 | PRSS1 (0.48) | PRSS1PRSS2PRSS3FURINF2 | |
| SCHEMBL27758947 | 0.78 | ALDH1A1 (0.50) | LMNAPRSS1PRSS2PRSS3FURIN | |
| SCHEMBL31493196 | 0.78 | ALDH1A1 (0.42) | F12ESR2ESR1CYP3A4CHRM1 | |
| SCHEMBL5952602 | 0.78 | MKNK1 (0.47) | HSD17B1 | |
| SCHEMBL28013376 | 0.77 | CES2 (0.54) | F12LMNAESR2ESR1CYP3A4 | |
| SCHEMBL8631612 | 0.77 | PRSS1 (0.45) | LMNAPRSS1PRSS2PRSS3FURIN | |
| SCHEMBL3951347 | 0.77 | PRSS1 (0.45) | PRSS1PRSS2PRSS3FURINF2 | |
| SCHEMBL2818302 | 0.75 | GAA (0.43) | LMNAESR2ESR1CYP3A4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143214-B | 3, 5-disubstituted-4, 5-dihydro-1, 2, 4-oxadiazoles for controlling nematode pests | 孟山都技术公司 | 2018-04-03 | — | — | CN | disclosed |