Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28289830 | 0.69 | — | — | |
| SCHEMBL28086053 | 0.68 | SIRT6 (0.30) | — | |
| SCHEMBL29210395 | 0.68 | — | — | |
| SCHEMBL1486699 | 0.68 | — | — | |
| SCHEMBL9523355 | 0.66 | — | — | |
| SCHEMBL28847539 | 0.65 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL7282705 | 0.63 | MAPT (0.30) | MAPT | |
| SCHEMBL28277334 | 0.62 | — | — | |
| SCHEMBL17229535 | 0.62 | SIRT2 (0.39) | ALDH1A1SIRT2NPC1POLBMAPT | |
| SCHEMBL15806427 | 0.62 | SIRT2 (0.39) | ALDH1A1SIRT2NPC1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105992768-B | The Imidazopyridazine compounds of conditioning agent as the response of IL 12, IL 23 and/or IFN α | 百时美施贵宝公司 | 2018-04-20 | — | — | CN | disclosed |