Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.41 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL369683 | 0.94 | SOS1 (0.40) | SOS1SOS2GNAI3GNAO1GNAI1 | |
| SCHEMBL28210516 | 0.93 | SOS1 (0.39) | SOS1SOS2GNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL6291188 | 0.90 | GNAO1 (0.40) | SOS1SOS2GNAI3GNAO1GNAI1 | |
| SCHEMBL27911334 | 0.87 | SOS1 (0.38) | SOS1SOS2GNAI3GNAO1GNAI1 | |
| SCHEMBL7025040 | 0.81 | GNAI3 (0.33) | GNAI3GNAO1GNAI1HSD17B10 | |
| SCHEMBL28142685 | 0.79 | SOS1 (0.47) | SOS1SOS2 | |
| SCHEMBL9236814 | 0.77 | GNAO1 (0.34) | SOS1SOS2GNAI3GNAO1GNAI1 | |
| SCHEMBL4893037 | 0.74 | GNAI3 (0.35) | GNAI3GNAO1GNAI1 | |
| SCHEMBL7029095 | 0.74 | GNAO1 (0.39) | GNAI3GNAO1GNAI1 | |
| SCHEMBL8817763 | 0.74 | GNAI3 (0.35) | GNAI3GNAO1GNAI1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107935943-A | Ester-water amphiphilic hypocrellin derivative and preparation method and application thereof | 中国科学院理化技术研究所 | 2018-04-20 | — | — | CN | disclosed |