Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.52 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29290724 | 0.92 | DRD2 (0.56) | DRD2CACNA1HTDP1SIGMAR1CD274 | |
| SCHEMBL2870818 | 0.88 | DRD2 (0.53) | DRD2CACNA1HTDP1SIGMAR1CD274 | |
| SCHEMBL31301242 | 0.84 | DRD2 (0.63) | DRD2CACNA1HTDP1SIGMAR1CD274 | |
| SCHEMBL1620776 | 0.83 | DRD2 (0.55) | DRD2CACNA1HTDP1SIGMAR1MEN1 | |
| SCHEMBL27655268 | 0.81 | DRD2 (0.60) | DRD2TDP1SIGMAR1MEN1GAA | |
| SCHEMBL24172673 | 0.81 | DRD2 (0.56) | DRD2CACNA1HTDP1SIGMAR1CD274 | |
| SCHEMBL31301250 | 0.81 | DRD2 (0.56) | DRD2CACNA1HTDP1SIGMAR1CD274 | |
| SCHEMBL4024516 | 0.81 | DRD2 (0.56) | DRD2CACNA1HTDP1MEN1GAA | |
| SCHEMBL7220892 | 0.80 | DRD2 (0.55) | DRD2CACNA1HTDP1MEN1KMT2A | |
| SCHEMBL485945 | 0.80 | DRD2 (0.55) | DRD2CACNA1HTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922394-A | 3 tetrazole radical benzene, 1,2 disulfonic acid amide derivative as metal beta lactamase restrainer | 默沙东公司 | 2018-04-17 | — | — | CN | disclosed |