Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2036528 | 0.82 | TSHR (0.59) | TSHRHTTPIK3CDKMT2ALMNA | |
| SCHEMBL11243429 | 0.79 | TSHR (0.56) | TSHRHTTPIK3CDKMT2ALMNA | |
| SCHEMBL9728160 | 0.78 | TSHR (0.51) | TSHRHTTPIK3CDKMT2ALMNA | |
| SCHEMBL5859538 | 0.77 | TSHR (0.33) | TSHRPIK3CDKMT2ALMNA | |
| SCHEMBL5799328 | 0.76 | TSHR (0.56) | TSHRHTTPIK3CDKMT2ALMNA | |
| SCHEMBL11516137 | 0.75 | TSHR (0.51) | TSHRHTTPIK3CDKMT2ALMNA | |
| SCHEMBL11512605 | 0.75 | TSHR (0.51) | TSHRHTTPIK3CDKMT2ALMNA | |
| SCHEMBL11516159 | 0.74 | TSHR (0.63) | TSHRHTTPIK3CDKMT2ALMNA | |
| SCHEMBL6935107 | 0.72 | TSHR (0.66) | TSHRHTTPIK3CDKMT2ALMNA | |
| SCHEMBL11515629 | 0.72 | TSHR (0.47) | TSHRHTTPIK3CDKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107936204-A | Polymer and nano-gel material and its preparation and application | 庄臣及庄臣视力保护公司 | 2018-04-20 | — | — | CN | claimed |