Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 11/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28211346 | 0.76 | CYP1A2 (0.49) | CYP3A4LMNAKDM4EMAPTALDH1A1 | |
| SCHEMBL5583851 | 0.73 | CYP2D6 (0.76) | CYP2D6CYP3A4NPC1RAB9AKDM4E | |
| SCHEMBL9151170 | 0.73 | CYP2D6 (0.76) | CYP2D6CYP3A4NPC1RAB9AKDM4E | |
| SCHEMBL28211344 | 0.72 | CYP1A2 (0.42) | NPC1RAB9ATSHRCYP19A1CYP2C9 | |
| SCHEMBL11588199 | 0.71 | CYP2D6 (0.56) | CYP2D6CYP3A4LMNANPY1RNPY2R | |
| SCHEMBL14129958 | 0.71 | CYP2D6 (1.00) | CYP2D6CYP3A4LMNANPC1RAB9A | |
| SCHEMBL26850 | 0.71 | LTA4H (0.70) | CYP2D6CYP3A4NPC1RAB9AHSD17B10 | |
| SCHEMBL6905782 | 0.69 | CYP2D6 (0.70) | CYP2D6CYP3A4NPC1RAB9AKDM4E | |
| SCHEMBL10022022 | 0.69 | CYP2D6 (0.70) | CYP2D6CYP3A4NPC1RAB9AKDM4E | |
| SCHEMBL28780750 | 0.69 | CYP2D6 (0.70) | CYP2D6CYP3A4NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922345-A | Arylsulfonamide compounds and its therapeutical uses as carbonic anhydrase inhibitor | 圣诺康生命科学公司 | 2018-04-17 | — | — | CN | claimed |
| CN-107922345-A | Arylsulfonamide compounds and its therapeutical uses as carbonic anhydrase inhibitor | 圣诺康生命科学公司 | 2018-04-17 | — | — | CN | disclosed |