Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 8/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28211346 | 0.81 | CYP1A2 (0.49) | CYP1A2CYP2C9CYP2C19CYP19A1MEN1 | |
| SCHEMBL28211347 | 0.72 | CYP2D6 (0.54) | CYP1A2CYP2C9CYP2C19CYP19A1TSHR | |
| SCHEMBL16076555 | 0.70 | KCNA3 (0.62) | CYP1A2CYP2C9CYP2C19CYP19A1MCHR1 | |
| SCHEMBL427889 | 0.70 | L3MBTL1 (0.53) | CYP1A2CYP2C9CYP2C19CYP19A1L3MBTL1 | |
| SCHEMBL255559 | 0.69 | L3MBTL1 (0.72) | CYP1A2CYP2C9CYP2C19CYP19A1L3MBTL1 | |
| SCHEMBL27731023 | 0.69 | LMNA (0.58) | CYP1A2CYP2C9CYP2C19L3MBTL1FAAH | |
| SCHEMBL9017760 | 0.69 | ELANE (0.67) | CYP1A2CYP2C9CYP2C19CYP19A1ELANE | |
| SCHEMBL7176779 | 0.69 | L3MBTL1 (0.53) | CYP1A2CYP2C9CYP2C19CYP19A1L3MBTL1 | |
| SCHEMBL12648399 | 0.69 | L3MBTL1 (0.51) | CYP1A2CYP2C9CYP2C19CYP19A1L3MBTL1 | |
| SCHEMBL13696485 | 0.69 | L3MBTL1 (0.51) | CYP1A2CYP2C9CYP2C19CYP19A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922345-A | Arylsulfonamide compounds and its therapeutical uses as carbonic anhydrase inhibitor | 圣诺康生命科学公司 | 2018-04-17 | — | — | CN | claimed |
| CN-107922345-A | Arylsulfonamide compounds and its therapeutical uses as carbonic anhydrase inhibitor | 圣诺康生命科学公司 | 2018-04-17 | — | — | CN | disclosed |