Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.56 |
| ▸ | PRNP | P04156 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5001108 | 0.83 | ALDH1A1 (0.67) | ALDH1A1KMT2ALMNASMN1; SMN2KDM4E | |
| SCHEMBL30583271 | 0.83 | ALDH1A1 (0.67) | ALDH1A1KMT2ALMNASMN1; SMN2KDM4E | |
| SCHEMBL10216426 | 0.80 | ALDH1A1 (0.63) | ALDH1A1KMT2ALMNASMN1; SMN2KDM4E | |
| SCHEMBL1241425 | 0.79 | ALDH1A1 (0.61) | ALDH1A1KMT2ALMNASMN1; SMN2KDM4E | |
| SCHEMBL10018544 | 0.77 | DPP4 (0.60) | ALDH1A1KMT2ALMNASMN1; SMN2KDM4E | |
| SCHEMBL29636198 | 0.77 | KDM4E (0.82) | ALDH1A1KMT2ALMNASMN1; SMN2KDM4E | |
| SCHEMBL5741498 | 0.76 | KDM4E (0.74) | ALDH1A1KMT2ALMNASMN1; SMN2KDM4E | |
| SCHEMBL1685948 | 0.76 | ALDH1A1 (0.77) | ALDH1A1KMT2ALMNASMN1; SMN2KDM4E | |
| SCHEMBL8358461 | 0.76 | MAPT (0.65) | ALDH1A1KMT2ALMNASMN1; SMN2KDM4E | |
| SCHEMBL10315671 | 0.76 | KDM4E (0.70) | ALDH1A1KMT2ALMNASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105384687-B | Quinolinones compound and its applied in medicine | 广东东阳光药业有限公司 | 2018-05-01 | — | — | CN | disclosed |