SCHEMBL30583271

SCHEMBL30583271

Cn1c(=O)c(O)c(O)c2ccccc21

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.67
KMT2A Q03164 5/20 0.67
LMNA P02545 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
KDM4E B2RXH2 10/20 0.61
HPGD P15428 4/20 0.61
RXFP1 Q9HBX9 2/20 0.61
PRNP P04156 1/20 0.58
GAA P10253 3/20 0.58
CYP2C19 P33261 2/20 0.58
HSD17B10 Q99714 2/20 0.58
GLA P06280 1/20 0.58
HTT P42858 1/20 0.58
MEN1 O00255 4/20 0.56
MAPT P10636 2/20 0.56
POLB P06746 2/20 0.56
PGR P06401 1/20 0.55
ERCC1 P07992 1/20 0.55
FEN1 P39748 1/20 0.55
ERCC4 Q92889 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5001108 1.00 ALDH1A1 (0.67) ALDH1A1KMT2ALMNASMN1; SMN2KDM4E
SCHEMBL10216426 0.89 ALDH1A1 (0.63) ALDH1A1KMT2ALMNASMN1; SMN2KDM4E
SCHEMBL1241425 0.83 ALDH1A1 (0.61) ALDH1A1KMT2ALMNASMN1; SMN2KDM4E
SCHEMBL28211432 0.83 ALDH1A1 (0.61) ALDH1A1KMT2ALMNASMN1; SMN2KDM4E
SCHEMBL10018544 0.82 DPP4 (0.60) ALDH1A1KMT2ALMNASMN1; SMN2KDM4E
SCHEMBL29636198 0.82 KDM4E (0.82) ALDH1A1KMT2ALMNASMN1; SMN2KDM4E
SCHEMBL2281039 0.80 ALDH1A1 (1.00) ALDH1A1KMT2ALMNASMN1; SMN2KDM4E
SCHEMBL14833431 0.80 ALDH1A1 (0.58) ALDH1A1KMT2ALMNASMN1; SMN2KDM4E
SCHEMBL7437202 0.80 ALDH1A1 (0.62) ALDH1A1KMT2ALMNASMN1; SMN2KDM4E
SCHEMBL14833430 0.80 ALDH1A1 (0.54) ALDH1A1KMT2ALMNASMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3681504-B1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ICAGEN INC (US) 2023-08-23 EP disclosed