Phenylthiourea

Phenylthiourea

SCHEMBL28211446

NC(=S)Nc1ccccc1.[Cu]

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.95
TAS2R38 P59533 3/20 0.95
HSD17B10 Q99714 2/20 0.95
TP53 P04637 1/20 0.95
TYR P14679 1/20 0.95
TSHR P16473 1/20 0.95
GAA P10253 5/20 0.63
CYP3A4 P08684 2/20 0.61
KMT2A Q03164 5/20 0.57
RAB9A P51151 3/20 0.56
MEN1 O00255 2/20 0.56
NPC1 O15118 2/20 0.56
NOX1 Q9Y5S8 1/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C9 P11712 1/20 0.56
HPGD P15428 1/20 0.56
ALOX12 P18054 1/20 0.56
CYP2C19 P33261 1/20 0.56
CYP1A2 P05177 1/20 0.55
PHGDH O43175 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylthiourea SCHEMBL22494152 1.00 ALDH1A1 (0.95) ALDH1A1TAS2R38HSD17B10TP53TYR
Phenylthiourea SCHEMBL11820844 0.97 ALDH1A1 (1.00) ALDH1A1TAS2R38HSD17B10TP53TYR
Phenylthiourea SCHEMBL42753 0.97 ALDH1A1 (1.00) ALDH1A1TAS2R38HSD17B10TP53TYR
Phenylthiourea SCHEMBL27472859 0.95 ALDH1A1 (0.95) ALDH1A1TAS2R38HSD17B10TP53TYR
Phenylthiourea SCHEMBL6644561 0.95 ALDH1A1 (0.95) ALDH1A1TAS2R38HSD17B10TP53TYR
Phenylthiourea SCHEMBL28966870 0.95 ALDH1A1 (0.95) ALDH1A1TAS2R38HSD17B10TP53TYR
Phenylthiourea SCHEMBL29672776 0.95 ALDH1A1 (0.95) ALDH1A1TAS2R38HSD17B10TP53TYR
Phenylthiourea SCHEMBL7814239 0.91 ALDH1A1 (0.86) ALDH1A1TAS2R38HSD17B10TP53TYR
SCHEMBL6926410 0.89 ALDH1A1 (0.83) ALDH1A1TAS2R38HSD17B10TP53TYR
Phenylthiourea SCHEMBL10948596 0.89 ALDH1A1 (0.83) ALDH1A1TAS2R38HSD17B10TP53TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107879447-A A kind of preparation method for being used to handle oil-polluted water flocculant 宁波科邦华诚技术转移服务有限公司 2018-04-06 CN disclosed