Phenylthiourea

Phenylthiourea

SCHEMBL42753

NC(=S)Nc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 1.00
TAS2R38 P59533 3/20 1.00
HSD17B10 Q99714 2/20 1.00
TP53 P04637 1/20 1.00
TYR P14679 1/20 1.00
TSHR P16473 1/20 1.00
GAA P10253 5/20 0.65
CYP3A4 P08684 2/20 0.64
KMT2A Q03164 5/20 0.59
RAB9A P51151 3/20 0.58
MEN1 O00255 2/20 0.58
NPC1 O15118 2/20 0.58
NOX1 Q9Y5S8 1/20 0.58
CYP2D6 P10635 1/20 0.58
CYP2C9 P11712 1/20 0.58
HPGD P15428 1/20 0.58
ALOX12 P18054 1/20 0.58
CYP2C19 P33261 1/20 0.58
CYP1A2 P05177 1/20 0.57
PHGDH O43175 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylthiourea SCHEMBL11820844 1.00 ALDH1A1 (1.00) ALDH1A1TAS2R38HSD17B10TP53TYR
Phenylthiourea SCHEMBL27472859 0.97 ALDH1A1 (0.95) ALDH1A1TAS2R38HSD17B10TP53TYR
Phenylthiourea SCHEMBL28211446 0.97 ALDH1A1 (0.95) ALDH1A1TAS2R38HSD17B10TP53TYR
Phenylthiourea SCHEMBL29672776 0.97 ALDH1A1 (0.95) ALDH1A1TAS2R38HSD17B10TP53TYR
Phenylthiourea SCHEMBL28966870 0.97 ALDH1A1 (0.95) ALDH1A1TAS2R38HSD17B10TP53TYR
Phenylthiourea SCHEMBL22494152 0.97 ALDH1A1 (0.95) ALDH1A1TAS2R38HSD17B10TP53TYR
Phenylthiourea SCHEMBL6644561 0.97 ALDH1A1 (0.95) ALDH1A1TAS2R38HSD17B10TP53TYR
Phenylthiourea SCHEMBL7814239 0.93 ALDH1A1 (0.86) ALDH1A1TAS2R38HSD17B10TP53TYR
SCHEMBL6926410 0.91 ALDH1A1 (0.83) ALDH1A1TAS2R38HSD17B10TP53TYR
Phenylthiourea SCHEMBL10948596 0.91 ALDH1A1 (0.83) ALDH1A1TAS2R38HSD17B10TP53TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6234 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122038280-A Construction and analysis method of zebra fish heart failure model 华南农业大学 2026-05-15 CN claimed
CN-122039176-A Conductive electroplating process of circuit carrier plate 深圳市则成电子股份有限公司 2026-05-15 CN claimed
CN-120966008-B Sulfone polymer and preparation method thereof 富海(东营)技术服务有限公司 2026-02-27 CN claimed
US-20250288624-A1 LONG-TERM STABILIZATION, FORMULATION AND TABLETING OF LIVE MICROBIAL CELLS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2025-09-18 US claimed
EP-3884921-B1 DENTAL POLYMERIZABLE COMPOSITION G C DENTAL IND CORP (JP) 2025-07-02 EP claimed
EP-3884922-B1 DENTAL POLYMERIZABLE COMPOSITION G C DENTAL IND CORP (JP) 2025-06-18 EP claimed
CN-120078892-A Application of bitter taste receptor 38/138 agonist in preparation of radiation injury prevention and treatment drugs 中国药科大学 2025-06-03 CN claimed
CN-120026380-A Sn-Ag micro-bump electroplating solution based on sulfonic acid system and preparation method and application thereof 大连理工大学 2025-05-23 CN claimed
EP-3816325-B1 ACIDIC AQUEOUS SILVER-NICKEL ALLOY ELECTROPLATING COMPOSITIONS AND METHODS DUPONT ELECTRONIC MAT INTERNATIONAL LLC (US) 2025-05-07 EP claimed
WO-2025086728-A1 COPPER PLATING SOLUTION, METALLIC COPPER LAYER COMPRISING SAME AND USE OF COPPER PLATING SOLUTION 江阴纳力新材料科技有限公司 2025-05-01 WO claimed
US-4080171-A Rapid analysis of trace components contained in a liquid SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1978-03-21 US claimed
US-4072712-A FROM ISOCYANATES, CATALYSIS BAYER AKTIENGESELLSCHAFT (DT) 1978-02-07 US claimed
US-4063014-A ANTIBIOTICS ABBOTT LABORATORIES (US) 1977-12-13 US claimed
US-4051026-A Recovery of silver from silver-containing solutions LEUVEN RESEARCH & DEVELOPMENT VZW (BE) 1977-09-27 US claimed
US-4035379-A Process for the production of 2-amino-benzothiazoles LONZA LTD. (CH) 1977-07-12 US claimed
US-3998894-A DIMERIZATION AND CYCLIZATION OF A STYRENE AND A HAL GENO-STYRENE BASF AKTIENGESELLSCHAFT (DT) 1976-12-21 US claimed
US-3991008-A METHACRYLATE MONOMER, HYDROPEROXIDE OXIDIZER, THIOUREA REDUCING AGENT THE KENDALL COMPANY (US) 1976-11-09 US claimed
US-3985782-A Phenylthiourea derivatives RHONE-POULENC S.A. (FR) 1976-10-12 US claimed
US-3977880-A Direct-positive emulsion containing silver halide grains internally doped with metal ions, surface ripened with gold and sulfur compound and fogged by light exposure FUJI PHOTO FILM CO., LTD. (JA) 1976-08-31 US claimed
US-3961049-A FUNGICIDES, MITICIDES KUMIAI CHEMICAL INDUSTRY CO., LTD. (JA) 1976-06-01 US claimed