Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7277972 | 0.94 | S1PR1 (0.49) | S1PR1S1PR3S1PR5S1PR4SPHK2 | |
| SCHEMBL7278231 | 0.94 | S1PR1 (0.49) | S1PR1S1PR3S1PR5S1PR4SPHK2 | |
| SCHEMBL856300 | 0.94 | S1PR1 (0.49) | S1PR1S1PR3S1PR5S1PR4SPHK2 | |
| SCHEMBL1906108 | 0.89 | S1PR1 (0.55) | S1PR1S1PR3S1PR5S1PR4SPHK2 | |
| SCHEMBL4372918 | 0.89 | S1PR1 (0.41) | S1PR1S1PR3S1PR5S1PR4SPHK2 | |
| SCHEMBL7269957 | 0.87 | S1PR1 (0.57) | S1PR1S1PR3S1PR5S1PR4SPHK2 | |
| SCHEMBL7269965 | 0.87 | S1PR1 (0.57) | S1PR1S1PR3S1PR5S1PR4SPHK2 | |
| SCHEMBL4370595 | 0.87 | S1PR1 (0.40) | S1PR1S1PR3S1PR5S1PR4SPHK2 | |
| SCHEMBL10220860 | 0.85 | S1PR1 (0.51) | S1PR1S1PR3S1PR5S1PR4SPHK2 | |
| SCHEMBL7029673 | 0.83 | S1PR1 (0.61) | S1PR1S1PR3S1PR5S1PR4SPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108290878-A | NOVEL FERROPORTIN INHIBITORS | 威佛（国际）股份公司 | 2018-07-17 | — | — | CN | disclosed |
| CN-107973789-A | A kind of epoxidized soybean oil toughener and its preparation method and application | 万华化学集团股份有限公司 | 2018-05-01 | — | — | CN | disclosed |