Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.49 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7277972 | 1.00 | S1PR1 (0.49) | S1PR1S1PR3S1PR5S1PR4SPHK2 | |
| SCHEMBL7278231 | 1.00 | S1PR1 (0.49) | S1PR1S1PR3S1PR5S1PR4SPHK2 | |
| SCHEMBL1906108 | 0.94 | S1PR1 (0.55) | S1PR1S1PR3S1PR5S1PR4SPHK2 | |
| SCHEMBL28211526 | 0.94 | S1PR1 (0.49) | S1PR1S1PR3S1PR5S1PR4SPHK2 | |
| SCHEMBL7269957 | 0.93 | S1PR1 (0.57) | S1PR1S1PR3S1PR5S1PR4SPHK2 | |
| SCHEMBL7269965 | 0.93 | S1PR1 (0.57) | S1PR1S1PR3S1PR5S1PR4SPHK2 | |
| SCHEMBL9155196 | 0.88 | S1PR1 (0.41) | S1PR1S1PR3S1PR5S1PR4SPHK2 | |
| SCHEMBL4375455 | 0.88 | S1PR1 (0.41) | S1PR1S1PR3S1PR5S1PR4SPHK2 | |
| SCHEMBL14509645 | 0.84 | ADRA1D (0.37) | S1PR1S1PR3S1PR5S1PR4SPHK2 | |
| SCHEMBL12643455 | 0.84 | S1PR1 (0.51) | S1PR1S1PR3S1PR5S1PR4SPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7211116-B2 | Hair dye composition | KAO CORPORATION (JP) | 2007-05-01 | — | — | US | claimed |
| EP-2432779-A1 | BENZOXAZEPINES BASED P13K/MT0R INHIBITORS AGAINST PROLIFERATIVE DISEASES | Exelixis, Inc. (US) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010135524-A1 | BENZOXAZEPINES BASED P13K/MT0R INHIBITORS AGAINST PROLIFERATIVE DISEASES | EXELIXIS, INC. (US) | 2010-11-25 | — | — | WO | disclosed |
| EP-1454617-B1 | HAIR BLEACH AND DYE COMPOSITIONS | KAO CORP (JP) | 2010-05-05 | — | — | EP | disclosed |
| EP-1454617-B1 | HAIR BLEACH AND DYE COMPOSITIONS | KAO CORP (JP) | 2010-05-05 | — | — | EP | disclosed |
| CN-100493488-C | Hair dye composition | KAO CORP (JP) | 2009-06-03 | — | — | CN | disclosed |
| US-7211116-B2 | Hair dye composition | KAO CORPORATION (JP) | 2007-05-01 | — | — | US | disclosed |
| US-7211116-B2 | Hair dye composition | KAO CORPORATION (JP) | 2007-05-01 | — | — | US | disclosed |
| US-7211116-B2 | Hair dye composition | KAO CORPORATION (JP) | 2007-05-01 | — | — | US | disclosed |
| CN-1691933-A | Hair dye composition | KAO CORP (JP) | 2005-11-02 | — | — | CN | disclosed |
| US-20050102770-A1 | Hair dye composition | KAO CORPORATION (JP) | 2005-05-19 | — | — | US | disclosed |
| EP-1454617-A1 | HAIR DYE COMPOSITION | Kao Corporation (JP) | 2004-09-08 | — | — | EP | disclosed |
| EP-0539281-B1 | Naphthamides, process for their preparation and their application in the therapeutical field | INST NAT SANTE RECH MED (FR) | 1998-12-30 | — | — | EP | disclosed |
| EP-0407137-B1 | Benzazine compounds and pharmaceutical uses thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1996-05-01 | — | — | EP | disclosed |
| US-5498628-A | ANTIPSYCHOTIC, PSYCHOSTIMULATORY, ANTIAUTISTIC, ANTIDEPRESSANT AND HYPOTENSIVE AGENTS, PARKINSON'S DISEASE | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1996-03-12 | — | — | US | disclosed |
| EP-0539281-A1 | New naphthamides, process for their preparation and their application in the therapeutical field | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1993-04-28 | — | — | EP | disclosed |
| US-5185333-A | Dopamine D2 receptor blocking agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1993-02-09 | — | — | US | disclosed |
| EP-0407137-A2 | Benzazine compounds and pharmaceutical uses thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-01-09 | — | — | EP | disclosed |
| EP-0124783-B1 | BENZOFURAN- AND BENZOPYRAN-CARBOXAMIDE DERIVATIVES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1987-12-09 | — | — | EP | disclosed |
| US-4617314-A | Benzofuran- and benzopyran-carboxamide derivatives | YOSHITOMI PHARMACEUTICAL INDUSTRIES LTD. (JP) | 1986-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050102770-A1 | Hair dye composition | DOHH, HADH, FAR1 | S1PR1 939/4885S1PR3 1234/4885S1PR5 1181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.