Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.30 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.30 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9801141 | 0.74 | ALOX15 (0.50) | ALOX15ACE2 | |
| SCHEMBL799862 | 0.73 | NCF1 (0.30) | — | |
| SCHEMBL9801382 | 0.71 | ALOX15 (0.46) | ALOX15GNAI3GNAO1GNAI1 | |
| SCHEMBL1424033 | 0.70 | ALOX15 (0.41) | ALOX15GNAI3GNAO1GNAI1 | |
| SCHEMBL23776337 | 0.68 | ALOX15 (0.43) | ALOX15GNAI3GNAO1GNAI1 | |
| SCHEMBL23478011 | 0.67 | MEN1 (0.33) | ALOX15 | |
| SCHEMBL29255685 | 0.65 | — | — | |
| SCHEMBL18426930 | 0.65 | CHRM1 (0.33) | — | |
| SCHEMBL17064241 | 0.65 | CHRM1 (0.33) | — | |
| SCHEMBL179843 | 0.65 | ALOX15 (1.00) | ALOX15ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107849024-A | With as indoleamine 2, the benzimidazole and imidazopyridine imido of 3 dioxygenase inhibitor activities are for benzamide compound | 吉利德科学公司 | 2018-03-27 | — | — | CN | disclosed |