Sugi Predict

Sugi Predict / Compounds / Trifluoroacetic Acid

Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL28211908

N=C(N)NCc1ccc(CCF)cc1.O=C(O)C(F)(F)F

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ TMPRSS6 Q8IU80 12/20 0.47
▸ F2 P00734 11/20 0.46
▸ HDAC3 O15379 1/20 0.42
▸ HDAC4 P56524 1/20 0.42
▸ HDAC1 Q13547 1/20 0.42
▸ HDAC6 Q9UBN7 1/20 0.42
▸ ST14 Q9Y5Y6 1/20 0.41
▸ ITGB1 P05556 2/20 0.40
▸ ITGA5 P08648 2/20 0.40
▸ ITGA4 P13612 2/20 0.40
▸ ITGB3 P05106 2/20 0.40
▸ ITGA2B P08514 1/20 0.40
▸ TPSAB1 Q15661 1/20 0.39
▸ FFAR1 O14842 1/20 0.39
▸ ITGB2 P05107 1/20 0.39
▸ ITGAV P06756 1/20 0.39
▸ ITGAL P20701 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL28814649 0.88 ST14 (0.47) TMPRSS6F2HDAC3HDAC4HDAC1
SCHEMBL16216331 0.87 ST14 (0.42) F2ST14ITGB3ITGA2BTPSAB1
SCHEMBL14764132 0.87 ST14 (0.42) F2ST14ITGB3ITGA2BTPSAB1
Trifluoroacetic Acid SCHEMBL17894376 0.85 ITGB1 (0.53) TMPRSS6F2HDAC3HDAC4HDAC1
Trifluoroacetic Acid SCHEMBL5447693 0.85 HTT (0.50) TMPRSS6F2
Trifluoroacetic Acid SCHEMBL30182377 0.85 ITGB1 (0.53) TMPRSS6F2HDAC3HDAC4HDAC1
Trifluoroacetic Acid SCHEMBL5172108 0.84 HDAC3 (0.52) TMPRSS6F2HDAC3HDAC4HDAC1
Formic Acid SCHEMBL29958755 0.83 ST14 (0.40) F2ST14ITGB3ITGA2BTPSAB1
Trifluoroacetic Acid SCHEMBL29958889 0.82 TMPRSS6 (0.39) TMPRSS6F2HDAC3HDAC4HDAC1
Trifluoroacetic Acid SCHEMBL28211814 0.80 ST14 (0.44) TMPRSS6F2HDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250170282-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS LANTHEUS MEDICAL IMAGING, INC. (US) 2025-05-29 — — US disclosed
US-20220339303-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS LANTHEUS MEDICAL IMAGING, INC. 2022-10-27 — — US disclosed
CN-108484449-A Composition, method and system for synthesizing and using developer 蓝瑟斯医学影像公司 2018-09-04 — — CN disclosed
CN-104159890-B Compositions, methods, and systems for synthesis and use of imaging agents 蓝瑟斯医学影像公司 2018-04-10 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250170282-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS FABP3, TNNI3, TNNT2 TMPRSS6 4586/4885F2 689/4885HDAC3 4032/4885
US-20220339303-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS FABP3, TNNI3, TNNT2 TMPRSS6 4586/4885F2 689/4885HDAC3 4032/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.