Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL29958889

N=C(N)NCc1ccc(CCF)c(Br)c1.O=C(O)C(F)(F)F

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TMPRSS6 Q8IU80 10/20 0.39
F2 P00734 10/20 0.38
F10 P00742 2/20 0.37
ITGB1 P05556 1/20 0.35
ITGA5 P08648 1/20 0.35
ITGA4 P13612 1/20 0.35
MLYCD O95822 1/20 0.33
HDAC3 O15379 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
NPY4R P50391 1/20 0.33
CTSD P07339 1/20 0.33
ITGB3 P05106 1/20 0.33
ITGA2B P08514 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL29959034 0.90 TMPRSS6 (0.40) TMPRSS6F2F10ITGB1ITGA5
SCHEMBL14764204 0.90 MLLT1 (0.31) F2F10
SCHEMBL19360091 0.90 MLLT1 (0.31) F2F10
Trifluoroacetic Acid SCHEMBL29958694 0.85 TMPRSS6 (0.36) TMPRSS6F2F10ITGB1ITGA5
Trifluoroacetic Acid SCHEMBL29958696 0.85 TMPRSS6 (0.36) TMPRSS6F2F10ITGB1ITGA5
SCHEMBL16218927 0.82
Trifluoroacetic Acid SCHEMBL28211908 0.82 TMPRSS6 (0.47) TMPRSS6F2ITGB1ITGA5ITGA4
SCHEMBL14764143 0.79 MLLT1 (0.32) F2F10CTSD
SCHEMBL16216372 0.79 MLLT1 (0.32) F2F10CTSD
SCHEMBL20852614 0.77 CYP2D6 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250170282-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS LANTHEUS MEDICAL IMAGING, INC. (US) 2025-05-29 US disclosed
US-20220339303-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS LANTHEUS MEDICAL IMAGING, INC. 2022-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250170282-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS FABP3, TNNI3, TNNT2 TMPRSS6 4586/4885F2 689/4885F10 761/4885
US-20220339303-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS FABP3, TNNI3, TNNT2 TMPRSS6 4586/4885F2 689/4885F10 761/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.