SCHEMBL28212

SCHEMBL28212

COC(=O)c1cccc(CBr)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 1/20 0.70
CYP4F2 P78329 3/20 0.68
CYP4A11 Q02928 3/20 0.68
SLC7A5 Q01650 1/20 0.59
MRGPRX4 Q96LA9 2/20 0.55
ALDH1A1 P00352 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
KDM4E B2RXH2 1/20 0.54
MAPT P10636 1/20 0.54
RAB9A P51151 1/20 0.54
HIF1A Q16665 1/20 0.52
TSHR P16473 1/20 0.52
HPGD P15428 1/20 0.51
FOLH1 Q04609 1/20 0.51
MEN1 O00255 1/20 0.50
NPC1 O15118 1/20 0.50
KMT2A Q03164 1/20 0.50
ABHD6 Q9BV23 1/20 0.49
MEP1B Q16820 1/20 0.49
HTT P42858 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29592260 1.00 LOXL2 (0.70) LOXL2CYP4F2CYP4A11SLC7A5MRGPRX4
Ammonia Solution, Strong SCHEMBL27820867 0.98 LOXL2 (0.68) LOXL2CYP4F2CYP4A11SLC7A5MRGPRX4
SCHEMBL30506526 0.90 CYP4F2 (0.66) LOXL2CYP4F2CYP4A11SLC7A5
SCHEMBL17164349 0.90 CYP4F2 (0.66) LOXL2CYP4F2CYP4A11SLC7A5
SCHEMBL1772530 0.89 LOXL2 (0.56) LOXL2CYP4F2CYP4A11SLC7A5MRGPRX4
SCHEMBL9875461 0.88 LOXL2 (0.56) LOXL2CYP4F2CYP4A11SLC7A5MRGPRX4
SCHEMBL244703 0.86 CYP4F2 (0.73) LOXL2CYP4F2CYP4A11SLC7A5MRGPRX4
SCHEMBL126284 0.85 LOXL2 (0.74) LOXL2CYP4F2CYP4A11SLC7A5MRGPRX4
SCHEMBL70173 0.85 CYP4F2 (0.83) LOXL2CYP4F2CYP4A11SLC7A5MRGPRX4
SCHEMBL10106423 0.85 LOXL2 (0.64) LOXL2CYP4F2CYP4A11SLC7A5MRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2850 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115959962-B Visible light-promoted halogenated alkane hydrodehalogenation method 中国科学院兰州化学物理研究所 2025-05-23 CN claimed
CN-119490643-A Preparation and application of coumestrol-based polyester and insulating heat-resistant material 武汉科技大学 2025-02-21 CN claimed
CN-119264013-A Preparation method of (1-arylmethyl-3-aryl-1-trifluoromethyl propyl) aromatic compound 南京工业大学 2025-01-07 CN claimed
EP-4452952-A1 A PREPARATION OF QUINAZOLINEDIONES AND USE THEREOF Council of Scientific and Industrial Research, an Indian Registered Body Incorporated under Regn. of Soc. Act (Act XXI of 1860) (IN) 2024-10-30 EP claimed
CN-116120261-B Preparation method of 3- [ (4-sulfadiazine-1-yl) methyl ] benzoic acid compound 浙大宁波理工学院 2024-01-23 CN claimed
WO-2023119320-A1 A PREPARATION OF QUINAZOLINEDIONES AND USE THEREOF COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860) (IN) 2023-06-29 WO claimed
CN-116120261-A Preparation method of 3- [ (4-sulfadiazine-1-yl) methyl ] benzoic acid compound 浙大宁波理工学院 2023-05-16 CN claimed
CN-108658834-B Preparation method of indolone derivative 烟台药物研究所 2021-03-23 CN claimed
CN-112341472-A Tyrosinase activated double-quenching diagnosis and treatment prodrug and preparation thereof 济南大学 2021-02-09 CN claimed
WO-2020114455-A1 QUINAZOLINE DIONE SALT COMPOUND CONTAINING PIPERAZINONE, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF 中国医学科学院药物研究所 2020-06-11 WO claimed
WO-2019196369-A1 THIAZOLO-PYRIMIDINE HIV-1 REVERSE TRANSCRIPTASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USES THEREOF 山东大学 2019-10-17 WO claimed
WO-2019196370-A1 FIVE-MEMBERED NON AROMATIC RING-PYRIMIDINE HIV-1 REVERSE TRANSCRIPTASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USES THEREOF 山东大学 2019-10-17 WO claimed
CN-108586471-A Furans simultaneously [3,2-d] miazines HIV-1 inhibitor and the preparation method and application thereof 山东大学 2018-09-28 CN claimed
CN-108440500-A A kind of quinazoline ditosylate salt HIV-1 inhibitor and its preparation method and application 山东大学 2018-08-24 CN claimed
CN-108409734-A Pyridopyrimidine class HIV-1 reverse transcriptase inhibitor and its preparation method and application 山东大学 2018-08-17 CN claimed
CN-108218896-A A kind of Thiazolopyrimidine HIV-1 reverse transcriptase inhibitor and its preparation method and application 山东大学 2018-06-29 CN claimed
CN-108218890-A A kind of five yuan of non-aromatic ring miazines HIV-1 reverse transcriptase inhibitor and its preparation method and application 山东大学 2018-06-29 CN claimed
CN-105899496-A OXAZOLIDINONE DERIVATIVES AS PPAR LIGANDS 安达卢西亚健康服务部 2016-08-24 CN claimed
US-20160152579-A1 OXAZOLIDINONE DERIVATIVES AS PPAR LIGANDS SERVICIO ANDALUZ DE SALUD (ES) 2016-06-02 US claimed
EP-3020710-A1 OXAZOLIDINONE DERIVATIVES AS PPAR LIGANDS Consejo Superior De Investigaciones Científicas (CSIC) (ES) 2016-05-18 EP claimed