Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 10/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | NQO1 | P15559 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MGMT | P16455 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17080260 | 0.84 | LMNA (0.38) | NAMPTACACBLMNAOPRM1 | |
| SCHEMBL28212014 | 0.76 | CYP3A4 (0.43) | NAMPTACACBCYP3A4 | |
| SCHEMBL17635681 | 0.75 | — | — | |
| SCHEMBL16687046 | 0.73 | NR4A2 (0.36) | NAMPTACACB | |
| SCHEMBL29881807 | 0.72 | NAMPT (0.47) | NAMPT | |
| SCHEMBL27279585 | 0.72 | ESR1 (0.35) | NAMPTACACBMGMT | |
| SCHEMBL18270917 | 0.72 | NQO1 (0.35) | NQO1LMNAALOX15 | |
| SCHEMBL9123636 | 0.71 | NQO1 (0.40) | NQO1MAPK1TDP1LMNAALDH1A1 | |
| SCHEMBL28309813 | 0.71 | — | — | |
| SCHEMBL113906 | 0.69 | ALDH1A1 (0.68) | MAPK1TDP1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107949558-B | Muscarinic agonists | 赫普泰雅治疗有限公司 | 2022-03-15 | — | — | CN | disclosed |
| CN-107949558-A | Muscarinic agonists | 赫普泰雅治疗有限公司 | 2018-04-20 | — | — | CN | disclosed |